SCHEMBL7644288

SCHEMBL7644288

CCCCCn1ccnc1-c1cccc2ccccc12

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 5/20 0.55
HTR2C P28335 2/20 0.48
CNR2 P34972 10/20 0.46
CNR1 P21554 4/20 0.46
HTR2A P28223 1/20 0.46
KMT2A Q03164 2/20 0.45
ALDH1A1 P00352 1/20 0.45
POLB P06746 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3399314 0.84 KMT2A (0.55) TLR8HTR2CHTR2AKMT2A
SCHEMBL14675363 0.80 TLR8 (0.48) TLR8KMT2AALDH1A1POLB
SCHEMBL14675685 0.80 TLR8 (0.48) TLR8KMT2AALDH1A1POLB
SCHEMBL3833947 0.77 ESR1 (0.59) TLR8KMT2AALDH1A1POLB
SCHEMBL5486071 0.76 HTR2C (0.66) HTR2CHTR2AKMT2AALDH1A1
SCHEMBL30641161 0.76 TLR8 (0.55) TLR8CNR2CNR1
SCHEMBL5612943 0.76 TLR8 (0.53) TLR8KMT2AALDH1A1POLB
Hexadecane SCHEMBL5816538 0.76 ESR1 (0.57) TLR8KMT2AALDH1A1POLB
SCHEMBL11016233 0.76 ESR1 (0.57) TLR8KMT2AALDH1A1POLB
SCHEMBL14675947 0.76 ESR1 (0.57) TLR8KMT2AALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6492076-B1 UNDERGOES CHANGE IN ELECTROMAGNETIC ABSORPTION WHEN HEATED; ANTIHALATION OR FILTER LAYERS CONTAINING ZWITTERIONIC 1-AMINOPYRIDINIUM DYE EASTMAN KODAK COMPANY 2002-12-10 US disclosed
US-6451516-B1 AMINOPYRIDINIUM DYE WITH METHIN LINKAGE TERMINATED BY A HETEROCVYCLIC NUCLEUS AS FOUND IN CYANINE DYES EASTMAN KODAK COMPANY 2002-09-17 US disclosed
EP-0050558-B1 PHOTOGRAPHIC EMULSIONS AND ELEMENTS CAPABLE OF FORMING DIRECT-POSITIVE IMAGES EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-07-17 EP disclosed
US-4306016-A HETEROCYCLIC CYANINE DYE-LIKE NUCLEATING AGENTS EASTMAN KODAK COMPANY (US) 1981-12-15 US disclosed
US-4110116-A Fogged direct positive silver halide emulsion containing a cyanine dye having at least one benzoxazole or benzothiazole nucleus substituted with halogen atoms MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1978-08-29 US disclosed
US-4075017-A Photothermographic material containing a combination of energy-sensitive organic dyes and process of forming a positive or negative image with the material EASTMAN KODAK COMPANY (US) 1978-02-21 US disclosed
US-4035190-A 2-ISOXAZOLIN-3-HETEROCYCLIC-SUBSTITUTED MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1977-07-12 US disclosed
US-4025347-A Fogged direct-positive silver halide emulsion containing a cyanine dye having an indole or indolenine nucleus substituted with a benzoyl or a phenylsulfonyl group MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1977-05-24 US disclosed
US-RE29168-E HEAT SENSITIVE, ANTIHALATION LAYER EASTMAN KODAK COMPANY (US) 1977-04-05 US disclosed
US-3970461-A Fogged, direct-positive silver halide emulsion containing carbocyanine dye having indolenine nucleus FUJI PHOTO FILM CO., LTD. (JA) 1976-07-20 US disclosed