SCHEMBL7644372

SCHEMBL7644372

C[Si](C)=[Zr](Cl)(Cl)(C1C=Cc2c(-c3cccc4ccccc34)cccc21)C1C=Cc2c(-c3cccc4ccccc34)cccc21

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.32
SLC6A4 P31645 2/20 0.31
EDNRB P24530 1/20 0.30
EDNRA P25101 1/20 0.30
KDM4E B2RXH2 1/20 0.30
TDP2 O95551 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
ALOX12 P18054 1/20 0.30
MAPK1 P28482 1/20 0.30
CASP3 P42574 1/20 0.30
HTT P42858 1/20 0.30
GALK1 P51570 1/20 0.30
BLM P54132 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
SENP8 Q96LD8 1/20 0.30
SENP7 Q9BQF6 1/20 0.30
SENP6 Q9GZR1 1/20 0.30
KDM4C Q9H3R0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7641966 0.95
SCHEMBL627681 0.82 CHRNB2 (0.30)
SCHEMBL674147 0.82 MAPT (0.31) KDM4ETDP2ALDH1A1MAPTHPGD
SCHEMBL7643029 0.80
SCHEMBL7149990 0.80 MAPT (0.32) KDM1ASLC6A4KDM4ETDP2ALDH1A1
SCHEMBL7636017 0.80
Hydrochloric Acid SCHEMBL674148 0.78 KDM4E (0.31) KDM1AKDM4ETDP2ALDH1A1MAPT
SCHEMBL5352320 0.77 MAPT (0.32) KDM4ETDP2ALDH1A1MAPTHPGD
SCHEMBL7641883 0.77
SCHEMBL339002 0.75 KDM1A (0.31) KDM1ASLC6A4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6472490-B1 AN ETHYLENE-AROMATIC VINYL COMPOUND COPOLYMER HAVING AN AROMATIC VINYL COMPOUND CONTENT OF FROM 1 TO LESS THAN 55% BY MOLAR FRACTION, WHICH HAS A HAZE OF AT MOST 41.5% WHEN MOLDED; METHINE DYES DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2002-10-29 US disclosed
US-6348556-B1 COORDINATION CATALYST OF TRANSITION METAL COMPLEX CONTAINING INDENYL GROUP(S) AND COCATALYST; ISOTACTIC; CATALYSIS, ADDITION COPOLYMERIZATION DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2002-02-19 US disclosed
US-6066709-A Ethylene-aromatic vinyl compound copolymer and method for its production DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2000-05-23 US disclosed
US-5883213-A STEREOREGULARITY DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1999-03-16 US disclosed