SCHEMBL7644579

SCHEMBL7644579

O=C(Nc1ncnc2c1ncn2[C@H]1C[C@H](O)[C@@H](COC(=O)OCCc2c(Cl)cccc2[N+](=O)[O-])O1)OCCc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 8/20 0.52
ADORA3 P0DMS8 1/20 0.36
ADORA1 P30542 1/20 0.36
CYP1A2 P05177 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7643482 0.83 P2RY2 (0.38) SLC29A1
SCHEMBL7644531 0.80 SLC29A1 (0.56) SLC29A1ADORA3ADORA1
SCHEMBL9565131 0.79 SLC29A1 (0.58) SLC29A1
SCHEMBL7896308 0.73 SLC29A1 (0.57) SLC29A1
SCHEMBL30205064 0.73 SLC29A1 (0.59) SLC29A1
SCHEMBL8914683 0.72 SLC29A1 (0.60) SLC29A1
SCHEMBL7040477 0.71 SLC29A1 (0.57) SLC29A1ADORA3
SCHEMBL5067228 0.71 DNMT1 (0.53) SLC29A1CYP1A2HPGD
SCHEMBL7643467 0.70 BCHE (0.47)
SCHEMBL13666500 0.70 BCHE (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0797580-B1 NUCLEOSIDE DERIVATIVES WITH PHOTOLABILE PROTECTIVE GROUPS PFLEIDERER WOLFGANG (DE) 2002-04-10 EP disclosed