Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7643577 | 0.86 | GSK3B (0.41) | LMNAALDH1A1 | |
| SCHEMBL778990 | 0.84 | CYP3A4 (0.53) | CYP3A4TSHRMEN1KMT2ALMNA | |
| SCHEMBL28661904 | 0.82 | TSHR (0.52) | CYP3A4TSHRMEN1KMT2ALMNA | |
| SCHEMBL16062705 | 0.82 | CYP3A4 (0.52) | CYP3A4TSHRMEN1KMT2ALMNA | |
| SCHEMBL7646578 | 0.81 | SRC (0.45) | MEN1KMT2A | |
| SCHEMBL28668996 | 0.81 | CYP3A4 (0.50) | CYP3A4TSHRMEN1KMT2ALMNA | |
| SCHEMBL7644588 | 0.78 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL7648390 | 0.78 | CYP3A4 (0.47) | CYP3A4TSHRMEN1KMT2ALMNA | |
| SCHEMBL28670766 | 0.78 | CYP3A4 (0.55) | CYP3A4TSHRMEN1KMT2ALMNA | |
| SCHEMBL777123 | 0.75 | CYP3A4 (0.61) | CYP3A4TSHRMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002008235-A1 | MEDICAMENT FOR ORAL APPLICATION, CONTAINING AMINOPROPYL PHOSPHONIC ACID ESTERS AS AN ACTIVE INGREDIENT | JOMAA PHARMAKA GMBH (DE) | 2002-01-31 | — | — | WO | disclosed |