Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8453775 | 0.85 | TSHR (0.58) | TSHRALDH1A1CYP3A4TP53HIF1A | |
| SCHEMBL12702085 | 0.84 | TSHR (0.61) | TSHRALDH1A1CYP3A4TP53HIF1A | |
| SCHEMBL12701651 | 0.83 | TSHR (0.55) | TSHRALDH1A1CYP3A4TP53HIF1A | |
| SCHEMBL29670983 | 0.83 | TSHR (0.56) | TSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL12701673 | 0.83 | TSHR (0.47) | TSHRALDH1A1CYP3A4TP53HIF1A | |
| SCHEMBL29670992 | 0.83 | TSHR (0.56) | TSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL12702116 | 0.83 | TSHR (0.47) | TSHRALDH1A1CYP3A4TP53HIF1A | |
| SCHEMBL12702118 | 0.83 | TSHR (0.47) | TSHRALDH1A1CYP3A4TP53HIF1A | |
| SCHEMBL6558984 | 0.83 | TSHR (0.56) | TSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL29670997 | 0.83 | TSHR (0.56) | TSHRALDH1A1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444724-B1 | SURFACE TREATMENT OF FILLER | BIOMAT SCIENCES, INC. | 2002-09-03 | — | — | US | disclosed |