SCHEMBL764547

SCHEMBL764547

OC[C@@H]1C[C@H](O)CN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1879074 1.00
SCHEMBL152150 1.00
SCHEMBL9203898 1.00
SCHEMBL2724423 1.00
SCHEMBL532330 1.00
SCHEMBL152149 1.00
SCHEMBL1870963 1.00
Hydrochloric Acid SCHEMBL1922314 0.97
Hydrochloric Acid SCHEMBL3442349 0.97
Hydrochloric Acid SCHEMBL15568382 0.97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12466815-B2 Carboxamide compounds and uses thereof INCYTE CORPORATION (US) 2025-11-11 US disclosed
US-20240150326-A1 CARBOXAMIDE COMPOUNDS AND USES THEREOF INCYTE CORPORATION 2024-05-09 US disclosed
CN-117486885-A Use of pyrazolopyrimidines 中国科学院上海药物研究所 2024-02-02 CN disclosed
US-20230265090-A1 QUINAZOLINE COMPOUND MEDSHINE DISCOVERY INC. (CN) 2023-08-24 US disclosed
US-20230265090-A1 QUINAZOLINE COMPOUND MEDSHINE DISCOVERY INC. (CN) 2023-08-24 US disclosed
EP-4186903-A1 QUINAZOLINE COMPOUND Medshine Discovery Inc. (CN) 2023-05-31 EP disclosed
WO-2023051628-A1 SOS1 INHIBITORS HAVING PYRIDO SIX-MEMBERED RING STRUCTURE 上海海和药物研究开发股份有限公司 2023-04-06 WO disclosed
EP-3774843-B1 DIPEPTIDE PIPERIDINE DERIVATIVES MOLECURE SA (PL) 2022-05-25 EP disclosed
EP-3755703-B1 N-(PHENYL)-2-(PHENYL)PYRIMIDINE-4-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS HPK1 INHIBITORS FOR TREATING CANCER INCYTE CORP (US) 2022-05-04 EP disclosed
EP-3774843-A1 DIPEPTIDE PIPERIDINE DERIVATIVES Oncoarendi Therapeutics SA (PL) 2021-02-17 EP disclosed
EP-1643998-B1 DUAL NK1/NK3 ANTAGONISTS FOR TREATING SCHIZOPHRENIA HOFFMANN LA ROCHE (CH) 2007-08-29 EP disclosed
EP-1643998-B1 DUAL NK1/NK3 ANTAGONISTS FOR TREATING SCHIZOPHRENIA HOFFMANN LA ROCHE (CH) 2007-08-29 EP disclosed
US-20070161620-A1 ISOQUINOLINE COMPOUND AND PHARMACEUTICAL USE THEREOF MITSUBISHI PHARMA CORPORATION (JP) 2007-07-12 US disclosed
US-7220759-B2 Isoquinoline compound and pharmaceutical use thereof MITSUBISHI PHARMA CORPORATION (JP) 2007-05-22 US disclosed
EP-1643998-A1 DUAL NK1/NK3 ANTAGONISTS FOR TREATING SCHIZOPHRENIA F. HOFFMANN-LA ROCHE AG (CH) 2006-04-12 EP disclosed
US-20050090533-A1 Dual NK1/NK3 receptor antagonists F. HOFMANN-LA ROCHE AG (CH) 2005-04-28 US disclosed
WO-2005002577-A1 DUAL NK1/NK3 ANTAGONISTS FOR TREATING SCHIZOPHRENIA F. HOFFMANN-LA ROCHE AG (CH) 2005-01-13 WO disclosed
US-20040248931-A1 Isoquinoline compound and pharmaceutical use thereof MITSUBISHI PHARMA CORPORATION (JP) 2004-12-09 US disclosed
US-6573377-B1 Antitumor agent capable of showing its efficacy even against 5- FU drug resistant tumors DAIICHI PHARMACEUTICALS CO., LTD. (JP) 2003-06-03 US disclosed
EP-1103551-A1 PYRAZOLE DERIVATIVES AND SALTS THEREOF DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2001-05-30 EP disclosed