⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1879074 | 1.00 | — | — | |
| SCHEMBL152150 | 1.00 | — | — | |
| SCHEMBL2724423 | 1.00 | — | — | |
| SCHEMBL764547 | 1.00 | — | — | |
| SCHEMBL532330 | 1.00 | — | — | |
| SCHEMBL152149 | 1.00 | — | — | |
| SCHEMBL1870963 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL1922314 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL3442349 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL15568382 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017048843-A1 | COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE ALAS1 GENE | ALNYLAM PHARMACEUTICALS, INC. (US) | 2017-03-23 | — | — | WO | disclosed |
| US-5419966-A | Solid support for synthesis of 3'-tailed oligonucleotides | MICROPROBE CORPORATION (US) | 1995-05-30 | — | — | US | disclosed |
| EP-0547142-A4 | — | MICROPROBE CORP (US) | 1995-01-18 | — | — | EP | disclosed |
| EP-0547142-A1 | SOLID SUPPORT SYNTHESIS OF 3'-TAILED OLIGONUCLEOTIDES VIA A LINKING MOLECULE | EPOCH PHARMACEUTICALS, INC. (US) | 1993-06-23 | — | — | EP | disclosed |
| WO-1992003464-A1 | SOLID SUPPORT SYNTHESIS OF 3'-TAILED OLIGONUCLEOTIDES VIA A LINKING MOLECULE | MICROPROBE CORPORATION (US) | 1992-03-05 | — | — | WO | disclosed |