⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL293018 | 1.00 | — | — | |
| SCHEMBL1691634 | 1.00 | — | — | |
| SCHEMBL893557 | 0.86 | — | — | |
| SCHEMBL893581 | 0.86 | — | — | |
| SCHEMBL17690276 | 0.86 | — | — | |
| SCHEMBL26805 | 0.84 | — | — | |
| SCHEMBL9831616 | 0.84 | KCNH2 (0.34) | — | |
| Hydrochloric Acid SCHEMBL31482227 | 0.84 | HRH3 (0.44) | — | |
| SCHEMBL902177 | 0.84 | GNAO1 (0.46) | — | |
| Hydrochloric Acid SCHEMBL4428244 | 0.84 | HRH3 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119613314-A | Buvaracetam Process for the preparation of intermediates | 浙江普洛家园药业有限公司 | 2025-03-14 | — | — | CN | claimed |
| CN-119350213-A | Synthesis method of (R) -4-propyl pyrrolidine-2-ketone | 诚达药业股份有限公司 | 2025-01-24 | — | — | CN | claimed |
| JP-2011524396-A | — | — | 2011-09-01 | — | — | JP | claimed |
| EP-2297096-A2 | ARYL KETONE AS MRI | F. Hoffmann-La Roche AG (CH) | 2011-03-23 | — | — | EP | claimed |
| US-20090318493-A1 | Aryl pyrrolidinyl and piperidinyl ketone derivatives and uses thereof | ROCHE PALO ALTO LLC | 2009-12-24 | — | — | US | claimed |
| WO-2009153178-A2 | ARYL KETONE AS MRI | F. HOFFMANN-LA ROCHE AG (CH) | 2009-12-23 | — | — | WO | claimed |
| CN-119613314-A | Buvaracetam Process for the preparation of intermediates | 浙江普洛家园药业有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-119613314-A | Buvaracetam Process for the preparation of intermediates | 浙江普洛家园药业有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-119350213-A | Synthesis method of (R) -4-propyl pyrrolidine-2-ketone | 诚达药业股份有限公司 | 2025-01-24 | — | — | CN | disclosed |
| CN-119350213-A | Synthesis method of (R) -4-propyl pyrrolidine-2-ketone | 诚达药业股份有限公司 | 2025-01-24 | — | — | CN | disclosed |
| CN-119350213-A | Synthesis method of (R) -4-propyl pyrrolidine-2-ketone | 诚达药业股份有限公司 | 2025-01-24 | — | — | CN | disclosed |
| CN-119303566-A | Preparation method of palladium-carbon catalyst for synthesizing buvaracetam intermediate | 浙江普洛家园药业有限公司 | 2025-01-14 | — | — | CN | disclosed |
| US-12018012-B2 | Aryl cyclopropyl-amino-isoquinolinyl amide compounds | AERIE PHARMACEUTICALS, INC. (US) | 2024-06-25 | — | — | US | disclosed |
| WO-2020151738-A1 | MACROCYCLIC FUSED PYRRAZOLES AS MCL-1 INHIBITORS | ASCENTAGE PHARMA (SUZHOU) CO., LTD. (CN) | 2020-07-30 | — | — | WO | disclosed |
| EP-1320540-B9 | PEPTIDOMIMETIC PROTEASE INHIBITORS | VERTEX PHARMA (US) | 2012-03-21 | — | — | EP | disclosed |
| US-20090318493-A1 | Aryl pyrrolidinyl and piperidinyl ketone derivatives and uses thereof | ROCHE PALO ALTO LLC | 2009-12-24 | — | — | US | disclosed |
| EP-1320540-B1 | PEPTIDOMIMETIC PROTEASE INHIBITORS | VERTEX PHARMA (US) | 2009-05-13 | — | — | EP | disclosed |
| US-7446195-B2 | High affinity thiophene-based and furan-based kinase ligands | SCHERING CORPORATION (US) | 2008-11-04 | — | — | US | disclosed |
| EP-1970377-A1 | LINCOMYCIN DERIVATIVE AND ANTIBACTERIAL AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2008-09-17 | — | — | EP | disclosed |
| US-20070043045-A1 | Novel high affinity thiophene-based and furan-based kinase ligands | SCHERING CORPORATION | 2007-02-22 | — | — | US | disclosed |