Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 11/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL909561 | 0.95 | TSHR (0.33) | TSHRTHRBFDPS | |
| SCHEMBL30403031 | 0.77 | TSHR (0.40) | TSHRTHRBFDPSGGPS1SMPD1 | |
| Bromide SCHEMBL28888844 | 0.75 | TSHR (0.38) | TSHRTHRBFDPSGGPS1SMPD1 | |
| SCHEMBL27932108 | 0.75 | TSHR (0.41) | TSHRTHRBFDPSGGPS1SMPD1 | |
| SCHEMBL414589 | 0.75 | TSHR (0.41) | TSHRTHRBFDPSGGPS1SMPD1 | |
| SCHEMBL29210027 | 0.74 | TSHR (0.42) | TSHRTHRBFDPSGGPS1SMPD1 | |
| SCHEMBL4457163 | 0.74 | TSHR (0.57) | TSHRTHRBFDPSGGPS1SMPD1 | |
| SCHEMBL5473271 | 0.72 | TSHR (0.47) | TSHRTHRBFDPSGGPS1SMPD1 | |
| Iodide SCHEMBL5089252 | 0.72 | TSHR (0.39) | TSHRTHRBFDPSGGPS1SMPD1 | |
| SCHEMBL11487921 | 0.72 | FDPS (0.44) | TSHRTHRBFDPSGGPS1SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476272-B1 | Organophosphines | RHODIA CONSUMER SPECIALTIES LIMITED (GB) | 2002-11-05 | — | — | US | disclosed |
| EP-1123302-A1 | ORGANOPHOSPHINES | Rhodia Consumer Specialties Limited (GB) | 2001-08-16 | — | — | EP | disclosed |
| WO-2000024752-A1 | ORGANOPHOSPHINES | ALBRIGHT & WILSON UK LIMITED (GB) | 2000-05-04 | — | — | WO | disclosed |