Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | DUT | P33316 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | RHEB | Q15382 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31573173 | 1.00 | TSHR (0.47) | TSHRERBB2DUTAKR1C3SRD5A2 | |
| SCHEMBL3243488 | 1.00 | TSHR (0.47) | TSHRERBB2DUTAKR1C3SRD5A2 | |
| SCHEMBL29750217 | 1.00 | TSHR (0.47) | TSHRERBB2DUTAKR1C3SRD5A2 | |
| SCHEMBL9753500 | 1.00 | TSHR (0.47) | TSHRERBB2DUTAKR1C3SRD5A2 | |
| SCHEMBL10889414 | 0.88 | SCN9A (0.38) | TSHRHTR2ASLC6A4LMNAL3MBTL1 | |
| SCHEMBL10890094 | 0.87 | KMT2A (0.39) | TSHRSLC6A4 | |
| SCHEMBL9814890 | 0.87 | SCN9A (0.39) | TSHRHTR2ASLC6A4L3MBTL1 | |
| SCHEMBL9814747 | 0.87 | SCN9A (0.39) | TSHRHTR2ASLC6A4L3MBTL1 | |
| SCHEMBL11316434 | 0.87 | TSHR (0.44) | TSHRSLC6A4LMNANPSR1PARP10 | |
| SCHEMBL8076731 | 0.85 | DUT (0.35) | ERBB2DUTSRD5A2TTRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957083-B1 | Process for stabilising cyanhydrines | DSM FINE CHEM AUSTRIA GMBH (AT) | 2002-04-10 | — | — | EP | claimed |
| US-6031123-A | Process for stabilizing cyanohydrins | DSM FINE CHEMICALS AUSTRIA GMBH (AT) | 2000-02-29 | — | — | US | claimed |
| EP-0573361-B1 | Process for the preparation of esters of 2,2-dimethyl-3-((Z)-2-(alkoxycarbonyl)ethenyl)cyclopropanecarboxylic acid and intermediates | ROUSSEL UCLAF (FR) | 1996-12-11 | — | — | EP | claimed |
| EP-0476708-B1 | (Trifluoromethyl)vinyl pyrethroid derivatives, their use as pesticides, process for their preparation, and intermediates of that process | ROUSSEL UCLAF (FR) | 1995-11-08 | — | — | EP | claimed |
| US-5312964-A | Process and intermediates | ROUSSEL UCLAF (FR) | 1994-05-17 | — | — | US | claimed |
| EP-0291626-A2 | Process for the preparation of optically-active cyanomethyl esters | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-11-23 | — | — | EP | claimed |
| US-4723027-A | TREATING AN ALDEHYDE WITH HYDROGEN CYANIDE IN THE PRESENCE OF CYCLO(D-PHENYLALANYL-D-HISTIDINE)CATALYST | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-02-02 | — | — | US | claimed |
| US-4594196-A | Reacting corresponding aldehyde with hydrogen cyanide in presence of aprotic solvent and catalyst | SHELL OIL COMPANY (US) | 1986-06-10 | — | — | US | claimed |
| US-4582646-A | REACTING A NON-SYMMETRICAL KETENE WITH A RACEMIC OR OPTICALLY ACTIVE ALPHA-HYDROXYNITRILE | SHELL OIL COMPANY (US) | 1986-04-15 | — | — | US | claimed |
| US-4560515-A | NON-SYMMETRICAL KETENE REACTED WITH A-HYDROXYNITRILE; TERTUARY AMINE CATALYST | SHELL OIL COMPANY (US) | 1985-12-24 | — | — | US | claimed |
| EP-0093664-B1 | ESTER OF CYCLOPROPANECARBOXYLIC ACID AND (S)-CYANO-(4-FLUORO-3-PHENOXYPHENYL)-METHYL ALCOHOL, ITS PREPARATION, ITS USE IN COMBATING PARASITES AND COMPOSITIONS CONTAINING IT | ROUSSEL-UCLAF (FR) | 1985-09-11 | — | — | EP | claimed |
| EP-0109909-B1 | DERIVATIVES OF 2,2-DIMETHYL-3-(2-FLUORO-3-OXO-3-(1,1-DIMETHYLETHOXY)-1-PROPENYL)CYCLOPROPANECARBOXYLIC ACID | ROUSSEL-UCLAF (FR) | 1985-08-21 | — | — | EP | claimed |
| EP-0109681-A2 | process for the preparation of optically-active cyanomethyl esters | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-05-30 | — | — | EP | claimed |
| EP-0022970-A2 | Stereoisomers of alpha-cyano-3-phenoxy-4-fluor-benzyl esters of 2,2-dimethyl-3-(2,2-dichloro-vinyl)-cyclopropane carboxylic acid, process for their preparation and their application as insecticides and acaricides | BAYER AG (DE) | 1981-01-28 | — | — | EP | claimed |
| US-6417377-B1 | Process for preparing enantiomer-enriched amino- and hydroxyfuranones | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2002-07-09 | — | — | US | disclosed |
| US-6225095-B1 | REACTING ALDEHYDE OR KETONE DISSOLVED IN AN ORGANIC, WATER-IMMISCIBLE OR SLIGHTLY MISCIBLE DILUENT, AN AQUEOUS HYDROXYNITRILE LYASE SOLUTION, AND A CYANIDE GROUP DONOR TO FORM AN EMULSION WHICH IS MAINTAINED BY STIRRING | DSM FINE CHEMICALS AUSTRIA GMBH (AT) | 2001-05-01 | — | — | US | disclosed |
| US-6031123-A | Process for stabilizing cyanohydrins | DSM FINE CHEMICALS AUSTRIA GMBH (AT) | 2000-02-29 | — | — | US | disclosed |
| EP-0046950-A1 | Optically active isomers of trans-3(2-(4-chlorophenyl)-vinyl)-2,2-dimethyl-cyclopropion-1-ic acid-(alpha-cyano-4-fluoro-3-phenoxy-benzyl)-esters, process for their preparation and their use as ectoparasiticides | BAYER AG (DE) | 1982-03-10 | — | — | EP | disclosed |
| US-4287208-A | ESPECIALLY USEFUL AGAINST INSECTS AND ACARIDS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-09-01 | — | — | US | disclosed |
| EP-0022970-A2 | Stereoisomers of alpha-cyano-3-phenoxy-4-fluor-benzyl esters of 2,2-dimethyl-3-(2,2-dichloro-vinyl)-cyclopropane carboxylic acid, process for their preparation and their application as insecticides and acaricides | BAYER AG (DE) | 1981-01-28 | — | — | EP | disclosed |