SCHEMBL7645757

SCHEMBL7645757

CCCCCCCCOc1ccc(-c2ccc(-c3ccc(CCCCCC)cc3)c(F)n2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.52
L3MBTL1 Q9Y468 3/20 0.52
RAB9A P51151 3/20 0.52
ALDH1A1 P00352 4/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
MEN1 O00255 1/20 0.50
USP2 O75604 1/20 0.50
LMNA P02545 1/20 0.50
CYP3A4 P08684 1/20 0.50
MAPK1 P28482 1/20 0.50
CASP1 P29466 1/20 0.50
KMT2A Q03164 1/20 0.50
SLCO1B3 Q9NPD5 1/20 0.50
SLCO1B1 Q9Y6L6 1/20 0.50
CASP3 P42574 1/20 0.49
SENP8 Q96LD8 1/20 0.49
SENP7 Q9BQF6 1/20 0.49
SENP6 Q9GZR1 1/20 0.49
KDM4E B2RXH2 3/20 0.47
HPGD P15428 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8504402 1.00 MAPT (0.52) MAPTL3MBTL1RAB9AALDH1A1SMN1; SMN2
SCHEMBL8506873 0.99 L3MBTL1 (0.51) MAPTL3MBTL1RAB9AALDH1A1SMN1; SMN2
SCHEMBL8506313 0.93 KDM4E (0.53) MAPTL3MBTL1RAB9AALDH1A1SMN1; SMN2
SCHEMBL7109780 0.90 RARB (0.50) MAPTL3MBTL1RAB9AALDH1A1SMN1; SMN2
SCHEMBL7112705 0.90 RARB (0.50) MAPTL3MBTL1RAB9AALDH1A1SMN1; SMN2
SCHEMBL7110624 0.90 RARB (0.50) MAPTL3MBTL1RAB9AALDH1A1SMN1; SMN2
SCHEMBL7114665 0.90 RARB (0.50) MAPTL3MBTL1RAB9AALDH1A1SMN1; SMN2
SCHEMBL7116062 0.90 RARB (0.50) MAPTL3MBTL1RAB9AALDH1A1SMN1; SMN2
SCHEMBL7115650 0.90 RARB (0.50) MAPTL3MBTL1RAB9AALDH1A1SMN1; SMN2
SCHEMBL7111254 0.90 RARB (0.50) MAPTL3MBTL1RAB9AALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6482479-B1 Active matrix displays having high contrast values CLARIANT INTERNATIONAL LTD. (CH) 2002-11-19 US disclosed
EP-1010692-A1 LIQUID-CRYSTAL COMPOUNDS HAVING LARGE VALUE OF PERMITTIVITY ANISOTROPY, LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME, AND LIQUID-CRYSTAL DISPLAY ELEMENT MADE USING THE LIQUID-CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 2000-06-21 EP disclosed