Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7644748 | 0.93 | TRPV1 (0.48) | TRPV1 | |
| SCHEMBL5566321 | 0.88 | TRPV1 (0.62) | TRPV1 | |
| SCHEMBL7649156 | 0.84 | TRPV1 (0.54) | TRPV1PTPN7DUSP3 | |
| SCHEMBL7644672 | 0.81 | TRPV1 (0.51) | TRPV1 | |
| SCHEMBL7648455 | 0.80 | TRPV1 (0.64) | TRPV1 | |
| SCHEMBL7862851 | 0.80 | TRPV1 (0.45) | TRPV1 | |
| SCHEMBL7855421 | 0.79 | TRPV1 (0.43) | TRPV1PTPN7DUSP3 | |
| SCHEMBL7644642 | 0.78 | TRPV1 (0.52) | TRPV1PTPN7DUSP3 | |
| SCHEMBL6305064 | 0.78 | TRPV1 (0.63) | TRPV1 | |
| SCHEMBL7644756 | 0.76 | TRPV1 (0.67) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476076-B1 | Vanilloid analogues containing resinferatoxin pharmacophores as potent vanilloid receptor agonists and analgesics, compositions and uses thereof | PACIFIC CORPORATION (KR) | 2002-11-05 | — | — | US | disclosed |
| EP-1154989-A1 | VANILLOID ANALOGUES CONTAINING RESINIFERATOXIN PHARMACOPHORES AS POTENT VANILLOID RECEPTOR AGONISTS AND ANALGESICS, COMPOSITIONS AND USES THEREOF | PACIFIC CORPORATION (KR) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000050387-A1 | VANILLOID ANALOGUES CONTAINING RESINIFERATOXIN PHARMACOPHORES AS POTENT VANILLOID RECEPTOR AGONISTS AND ANALGESICS, COMPOSITIONS AND USES THEREOF | PACIFIC CORPORATION (KR) | 2000-08-31 | — | — | WO | disclosed |