SCHEMBL5566321

SCHEMBL5566321

COc1cc(CNC(=S)CC(COC(=O)C(C)(C)C)Cc2ccc(C)c(C)c2)ccc1O

nearest known ligand 0.79

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 3/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6305064 0.90 TRPV1 (0.63) TRPV1
SCHEMBL7644763 0.89 TRPV1 (0.67) TRPV1
SCHEMBL7644756 0.89 TRPV1 (0.67) TRPV1
SCHEMBL29809933 0.89 TRPV1 (0.79) TRPV1
SCHEMBL93907 0.89 TRPV1 (0.79) TRPV1
SCHEMBL7646868 0.88 TRPV1 (0.79) TRPV1
SCHEMBL7643950 0.88 TRPV1 (0.66) TRPV1
SCHEMBL7645834 0.88 TRPV1 (0.47) TRPV1
SCHEMBL7644748 0.86 TRPV1 (0.48) TRPV1
SCHEMBL6305058 0.84 TRPV1 (0.56) TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050031717-A1 Using capsaicin receptors; complexing VIRGINIA COMMONWEALTH UNIVERSITY 2005-02-10 US claimed
WO-2005006881-A2 SALT TASTE MODIFICATION VIRGINIA COMMONWEALTH UNIVERSITY (US) 2005-01-27 WO claimed
US-12419815-B2 Microcapsule compositions stabilized with viscosity control agents INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2025-09-23 US disclosed
US-12324452-B2 Delivery systems and methods of preparing the same INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2025-06-10 US disclosed
CN-116764558-A Microcapsule compositions stabilized with viscosity control agents 国际香料和香精公司 2023-09-19 CN disclosed
EP-4209264-A1 MICROCAPSULE COMPOSITIONS STABILIZED WITH VISCOSITY CONTROL AGENTS International Flavors & Fragrances Inc. (US) 2023-07-12 EP disclosed
CN-109689197-B Microcapsule compositions stabilized with viscosity control agents 国际香料和香精公司 2023-06-23 CN disclosed
EP-3512625-B1 MICROCAPSULE COMPOSITIONS STABILIZED WITH VISCOSITY CONTROL AGENTS INT FLAVORS & FRAGRANCES INC (US) 2023-04-26 EP disclosed
US-20210212352-A1 DELIVERY SYSTEMS AND METHODS OF PREPARING THE SAME INTERNATIONAL FLAVORS & FRAGRANCES INC. 2021-07-15 US disclosed
US-10993466-B2 Delivery systems and methods of preparing the same INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2021-05-04 US disclosed
EP-3285594-B1 DELIVERY SYSTEMS AND METHODS OF PREPARING THE SAME INT FLAVORS & FRAGRANCES INC (US) 2021-03-17 EP disclosed
WO-2018053356-A1 MICROCAPSULE COMPOSITIONS STABILIZED WITH VISCOSITY CONTROL AGENTS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2018-03-22 WO disclosed
EP-3285594-A1 DELIVERY SYSTEMS AND METHODS OF PREPARING THE SAME International Flavors & Fragrances Inc. (US) 2018-02-28 EP disclosed
WO-2016172699-A1 DELIVERY SYSTEMS AND METHODS OF PREPARING THE SAME INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2016-10-27 WO disclosed
WO-2005006881-A3 SALT TASTE MODIFICATION UNIV VIRGINIA COMMONWEALTH (US) 2007-02-08 WO disclosed
US-20050031717-A1 Using capsaicin receptors; complexing VIRGINIA COMMONWEALTH UNIVERSITY 2005-02-10 US disclosed
US-20050031717-A1 Using capsaicin receptors; complexing VIRGINIA COMMONWEALTH UNIVERSITY 2005-02-10 US disclosed
WO-2005006881-A2 SALT TASTE MODIFICATION VIRGINIA COMMONWEALTH UNIVERSITY (US) 2005-01-27 WO disclosed
WO-2005006881-A2 SALT TASTE MODIFICATION VIRGINIA COMMONWEALTH UNIVERSITY (US) 2005-01-27 WO disclosed
US-6476076-B1 Vanilloid analogues containing resinferatoxin pharmacophores as potent vanilloid receptor agonists and analgesics, compositions and uses thereof PACIFIC CORPORATION (KR) 2002-11-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210212352-A1 DELIVERY SYSTEMS AND METHODS OF PREPARING THE SAME MAL2, TAS2R42, TAS2R31 TRPV1 749/4885
US-12324452-B2 Delivery systems and methods of preparing the same MAL2, TAS2R42, TAS2R31 TRPV1 749/4885
US-12419815-B2 Microcapsule compositions stabilized with viscosity control agents ACR, ALG1, MLEC TRPV1 3271/4885
US-10993466-B2 Delivery systems and methods of preparing the same MAL2, TAS2R42, TAS2R31 TRPV1 749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.