SCHEMBL7645957

SCHEMBL7645957

CCCC(CC)C[N]CC

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.32
TDP1 Q9NUW8 1/20 0.32
TSHR P16473 2/20 0.31
CYP3A4 P08684 2/20 0.31
USP2 O75604 3/20 0.31
MEN1 O00255 2/20 0.31
TP53 P04637 2/20 0.31
KMT2A Q03164 2/20 0.31
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31
BCL2L1 Q07817 3/20 0.30
BAK1 Q16611 3/20 0.30
ALOX15 P16050 1/20 0.30
MAPK1 P28482 1/20 0.30
HTT P42858 1/20 0.30
BLM P54132 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5932799 0.89 ALDH1A1 (0.35) ALDH1A1TDP1TSHRCYP3A4USP2
SCHEMBL3383370 0.85 ALDH1A1 (0.50) ALDH1A1TDP1TSHRCYP3A4USP2
SCHEMBL6418725 0.83
SCHEMBL5932389 0.77 CA12 (0.32) TSHR
SCHEMBL18428600 0.76
SCHEMBL9212061 0.75 USP2 (0.44) ALDH1A1TDP1TSHRCYP3A4USP2
SCHEMBL13248698 0.74
SCHEMBL10306788 0.74
SCHEMBL1052649 0.74 ALDH1A1 (0.54) ALDH1A1TDP1TSHRCYP3A4USP2
SCHEMBL4279899 0.74 ALDH1A1 (0.39) ALDH1A1TDP1TSHRCYP3A4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1250363-A2 CHEMICAL COMPOUND, METHOD FOR THE PRODUCTION THEREOF AND ITS USE IN CATALYST SYSTEMS FOR PRODUCING POLYOLEFINS Basell Polyolefine GmbH (DE) 2002-10-23 EP disclosed
WO-2001048035-A2 CHEMICAL COMPOUND, METHOD FOR THE PRODUCTION THEREOF AND ITS USE IN CATALYST SYSTEMS FOR PRODUCING POLYOLEFINS BASELL POLYOLEFINE GMBH (DE) 2001-07-05 WO disclosed