Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9197055 | 0.82 | ALDH1A1 (0.56) | ALDH1A1SIGMAR1LMNAKMT2ACYP3A4 | |
| SCHEMBL507933 | 0.81 | CHRM3 (0.63) | ALDH1A1CHRM3 | |
| Hydrochloric Acid SCHEMBL9197626 | 0.81 | ALDH1A1 (0.59) | ALDH1A1SIGMAR1LMNAKMT2ACYP3A4 | |
| Hydrochloric Acid SCHEMBL9190355 | 0.80 | CHRM3 (0.61) | ALDH1A1CHRM3 | |
| SCHEMBL8033956 | 0.80 | ALDH1A1 (0.72) | ALDH1A1SIGMAR1LMNAKMT2ACYP3A4 | |
| SCHEMBL21044023 | 0.80 | ALDH1A1 (0.72) | ALDH1A1SIGMAR1LMNAKMT2ACYP3A4 | |
| SCHEMBL2717435 | 0.80 | ALDH1A1 (0.72) | ALDH1A1SIGMAR1LMNAKMT2ACYP3A4 | |
| SCHEMBL16641754 | 0.80 | ALDH1A1 (0.72) | ALDH1A1SIGMAR1LMNAKMT2ACYP3A4 | |
| SCHEMBL13592179 | 0.79 | CHRM2 (0.54) | ALDH1A1CHRM3SIGMAR1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL9192396 | 0.79 | CHRM3 (0.64) | ALDH1A1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6482837-B1 | Antimuscarinic compounds and methods for treatment of bladder diseases | UNIVERSITY OF ROCHESTER | 2002-11-19 | — | — | US | disclosed |