Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 17/20 | 0.74 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7678814 | 0.90 | MCHR1 (0.73) | MCHR1HTR2CKDR | |
| SCHEMBL6925692 | 0.89 | MCHR1 (0.92) | MCHR1HTR2C | |
| SCHEMBL7913510 | 0.88 | MCHR1 (0.66) | MCHR1HTR2CKDR | |
| SCHEMBL6926020 | 0.87 | MCHR1 (0.80) | MCHR1HTR2C | |
| SCHEMBL6923388 | 0.84 | MCHR1 (0.75) | MCHR1HTR2C | |
| SCHEMBL6925343 | 0.83 | MCHR1 (0.77) | MCHR1HTR2CKDR | |
| SCHEMBL6921907 | 0.82 | MCHR1 (0.80) | MCHR1HTR2C | |
| SCHEMBL7922186 | 0.82 | MCHR1 (0.69) | MCHR1HTR2CKDR | |
| SCHEMBL6921439 | 0.81 | MCHR1 (0.78) | MCHR1HTR2CKDR | |
| SCHEMBL6927209 | 0.81 | MCHR1 (0.78) | MCHR1HTR2CKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002511879-A | — | — | 2002-04-16 | — | — | JP | claimed |
| EP-1001766-A4 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2001-04-04 | — | — | EP | claimed |
| EP-1001766-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-05-24 | — | — | EP | claimed |
| WO-1999001127-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-01-14 | — | — | WO | claimed |