Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | RARA | P10276 | 3/20 | 0.37 |
| ▸ | RARB | P10826 | 3/20 | 0.37 |
| ▸ | RARG | P13631 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7530264 | 0.94 | APP (0.38) | APPPTPN1PTPN2PTPN6NR1H4 | |
| SCHEMBL7534171 | 0.92 | NOTUM (0.46) | APPPTPN1PTPN2PTPN6NR1H4 | |
| SCHEMBL7530259 | 0.85 | APP (0.40) | APPPTPN1PTPN2PTPN6MAPT | |
| SCHEMBL7530268 | 0.85 | APP (0.40) | APPPTPN1PTPN2PTPN6MAPT | |
| SCHEMBL7650125 | 0.81 | PTPN1 (0.61) | APPPTPN1PTPN2PTPN6RARA | |
| SCHEMBL7523901 | 0.78 | PTPN1 (0.47) | APPPTPN1PTPN2PTPN6MAPT | |
| SCHEMBL7534165 | 0.78 | PTPN1 (0.44) | APPPTPN1PTPN2PTPN6MAPT | |
| SCHEMBL7648645 | 0.78 | PTPN1 (0.44) | APPPTPN1PTPN2PTPN6MAPT | |
| SCHEMBL7648595 | 0.76 | MAPT (0.40) | MAPTMAPK1HSD17B10TDP1NPC1 | |
| SCHEMBL7531123 | 0.76 | PTPN1 (0.53) | APPPTPN1PTPN2PTPN6RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479548-B2 | P-(BENZOYLAMINO)STILBENE DERIVATIVES | TELIK, INC. | 2002-11-12 | — | — | US | disclosed |