Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.61 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.61 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.61 |
| ▸ | HNF4A | P41235 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 6/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | RARA | P10276 | 2/20 | 0.43 |
| ▸ | RARB | P10826 | 2/20 | 0.43 |
| ▸ | RARG | P13631 | 2/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7531123 | 0.93 | PTPN1 (0.53) | PTPN1PTPN2PTPN6HNF4APTGS2 | |
| SCHEMBL7523901 | 0.84 | PTPN1 (0.47) | PTPN1PTPN2PTPN6HNF4AAPP | |
| SCHEMBL7531117 | 0.83 | PTPN1 (0.63) | PTPN1PTPN2PTPN6HNF4APTGS2 | |
| SCHEMBL7531126 | 0.83 | PTPN1 (0.63) | PTPN1PTPN2PTPN6HNF4APTGS2 | |
| SCHEMBL12881125 | 0.82 | PTPN1 (0.75) | PTPN1PTPN2PTPN6HNF4APTGS2 | |
| SCHEMBL7646325 | 0.81 | APP (0.41) | PTPN1PTPN2PTPN6HNF4APTGS2 | |
| SCHEMBL7528663 | 0.79 | SNCA (0.49) | PTPN1HNF4AAPPDHODH | |
| SCHEMBL6266629 | 0.78 | PTPN1 (1.00) | PTPN1PTPN2PTPN6HNF4APTGS2 | |
| SCHEMBL6266631 | 0.78 | PTPN1 (1.00) | PTPN1PTPN2PTPN6HNF4APTGS2 | |
| SCHEMBL1048686 | 0.78 | PTPN1 (1.00) | PTPN1PTPN2PTPN6HNF4APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479548-B2 | P-(BENZOYLAMINO)STILBENE DERIVATIVES | TELIK, INC. | 2002-11-12 | — | — | US | disclosed |