SCHEMBL7646336

SCHEMBL7646336

CC(C)(C)C(=O)SCCOP(=O)(CCCBr)OCCSC(=O)C(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
BTN3A1 O00481 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7645867 0.82 CA12 (0.34) CA12CA1CA2CA9
SCHEMBL28587893 0.77 CA12 (0.41) CA12CA1CA2CA9
SCHEMBL5077985 0.75 CA12 (0.40) CA12CA1CA2CA9BTN3A1
SCHEMBL14086322 0.75 CA12 (0.40) CA12CA1CA2CA9
Hydrochloric Acid SCHEMBL28609025 0.74 CA12 (0.39) CA12CA1CA2CA9BTN3A1
SCHEMBL15634387 0.74 CA12 (0.39) CA12CA1CA2CA9
SCHEMBL25821319 0.74 CA12 (0.39) CA12CA1CA2CA9
SCHEMBL7651071 0.73 HDAC6 (0.34)
SCHEMBL7647689 0.72 PTGS2 (0.36) CA2
SCHEMBL17036885 0.72 CA12 (0.44) CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002008235-A1 MEDICAMENT FOR ORAL APPLICATION, CONTAINING AMINOPROPYL PHOSPHONIC ACID ESTERS AS AN ACTIVE INGREDIENT JOMAA PHARMAKA GMBH (DE) 2002-01-31 WO disclosed