Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | PREP | P48147 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1010269 | 0.84 | CYP1A2 (0.54) | CHRM2CHRM1CHRM3PREPCYP1A2 | |
| SCHEMBL7247150 | 0.83 | CHRM2 (0.48) | CHRM2CHRM1CHRM3PREPABCB1 | |
| SCHEMBL22000397 | 0.83 | CHRM2 (0.49) | CHRM2CHRM1CHRM3PREPGPR119 | |
| SCHEMBL13480843 | 0.81 | CHRM2 (0.50) | CHRM2CHRM1CHRM3PREPGPR119 | |
| SCHEMBL19570649 | 0.78 | CHRM2 (0.55) | CHRM2CHRM1CHRM3PREPGPR119 | |
| SCHEMBL3091698 | 0.78 | CHRM2 (0.55) | CHRM2CHRM1CHRM3PREPGPR119 | |
| SCHEMBL23264873 | 0.77 | CHRM2 (0.53) | CHRM2CHRM1CHRM3PREPGPR119 | |
| SCHEMBL3866475 | 0.76 | CYP1A2 (0.49) | CHRM2CHRM1CHRM3PREPCYP1A2 | |
| SCHEMBL13480844 | 0.75 | CHRM2 (0.45) | CHRM2CHRM1CHRM3PREPGPR119 | |
| SCHEMBL797568 | 0.75 | CHRM2 (0.46) | CHRM2CHRM1CHRM3PREPCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6486323-B1 | Process for producing optically active tropinonemonocarboxylic acid derivative | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2002-11-26 | — | — | US | disclosed |