SCHEMBL7247150

SCHEMBL7247150

CC(C)(C)OC(=O)N1[C@H]2CC[C@@H]1C(C(=O)O)C(=O)C2

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.48
CHRM1 P11229 1/20 0.48
CHRM3 P20309 1/20 0.48
PREP P48147 4/20 0.40
HSD11B1 P28845 1/20 0.38
GPR119 Q8TDV5 2/20 0.36
ABCB1 P08183 1/20 0.34
AGTR2 P50052 1/20 0.34
DDB1 Q16531 2/20 0.33
CRBN Q96SW2 2/20 0.33
HSD17B10 Q99714 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.33
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29642341 0.86 CHRM2 (0.46) CHRM2CHRM1CHRM3PREPHSD11B1
SCHEMBL1012317 0.86 CHRM2 (0.46) CHRM2CHRM1CHRM3PREPHSD11B1
SCHEMBL15239620 0.86 CHRM2 (0.46) CHRM2CHRM1CHRM3PREPHSD11B1
SCHEMBL797568 0.86 CHRM2 (0.46) CHRM2CHRM1CHRM3PREPHSD11B1
SCHEMBL24701533 0.85 CHRM2 (0.44) CHRM2CHRM1CHRM3PREPHSD11B1
SCHEMBL7646464 0.83 CHRM2 (0.46) CHRM2CHRM1CHRM3PREPHSD11B1
SCHEMBL31080245 0.82 CHRM2 (0.50) CHRM2CHRM1CHRM3PREPHSD11B1
SCHEMBL31080149 0.82 CHRM2 (0.50) CHRM2CHRM1CHRM3PREPHSD11B1
SCHEMBL31080086 0.82 CHRM2 (0.50) CHRM2CHRM1CHRM3PREPHSD11B1
SCHEMBL21124699 0.82 CHRM2 (0.50) CHRM2CHRM1CHRM3PREPHSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030065183-A1 Process for producing optically active tropinonemonocarboxylic acid ester derivative NIHON MEDI-PHYSICS CO., LTD. 2003-04-03 US claimed
EP-1118674-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE TROPINONE MONOCARBOXYLIC ACID DERIVATIVE Nihon Medi-Physics Co., Ltd. (JP) 2001-07-25 EP claimed
US-20030065183-A1 Process for producing optically active tropinonemonocarboxylic acid ester derivative NIHON MEDI-PHYSICS CO., LTD. 2003-04-03 US disclosed
US-6486323-B1 Process for producing optically active tropinonemonocarboxylic acid derivative NIHON MEDI-PHYSICS CO., LTD. (JP) 2002-11-26 US disclosed
EP-1118674-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE TROPINONE MONOCARBOXYLIC ACID DERIVATIVE Nihon Medi-Physics Co., Ltd. (JP) 2001-07-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030065183-A1 Process for producing optically active tropinonemonocarboxylic acid ester derivative CES2, FTO, HAAO CHRM2 733/4885CHRM1 412/4885CHRM3 707/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.