Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7644298 | 0.90 | PNMT (0.48) | PNMTNPC1RAB9AGABRA1GABRB2 | |
| SCHEMBL3366575 | 0.87 | PNMT (0.48) | PNMTNPC1RAB9AHTR2BHTR7 | |
| SCHEMBL20640668 | 0.87 | PNMT (0.50) | PNMTNPC1RAB9AHTR2BALDH1A1 | |
| SCHEMBL27685457 | 0.86 | PNMT (0.47) | PNMTNPC1RAB9AGABRA1GABRB2 | |
| SCHEMBL27704506 | 0.84 | PNMT (0.48) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL20640473 | 0.84 | PNMT (0.44) | PNMTNPC1RAB9AGABRA1GABRB2 | |
| SCHEMBL8681679 | 0.83 | PNMT (0.40) | PNMTNPC1RAB9AGABRA1GABRB2 | |
| SCHEMBL30606684 | 0.82 | PNMT (0.68) | PNMTNPC1RAB9AGABRA1GABRB2 | |
| SCHEMBL633763 | 0.82 | PNMT (0.68) | PNMTNPC1RAB9AGABRA1GABRB2 | |
| SCHEMBL27493132 | 0.82 | PNMT (0.46) | PNMTNPC1RAB9AGABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6468589-B2 | A HEAT-CURED POLYETHER BASED ON A 9,9-BIS(P-HYDROXYPHENYL)-FLUORENE HAVING AT LEAST ONE ALKYL SUBSTITUENT AND A DIHYDROXY AROMATIC COMONOMER; LOW DIELECTRIC PROTECTIVE COATINGS; HEAT RESISTANCE; NONCRACKING | JSR CORPORATION (JP) | 2002-10-22 | — | — | US | disclosed |
| US-20010012870-A1 | Composition for film formation and insulating film | JSR CORPORATION (JP) | 2001-08-09 | — | — | US | disclosed |