Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 11/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.47 |
| ▸ | CTRC | Q99895 | 3/20 | 0.47 |
| ▸ | F10 | P00742 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.46 |
| ▸ | PKLR | P30613 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6752123 | 0.87 | F2 (0.49) | F2PRSS2CTRCF10 | |
| Hydrochloric Acid SCHEMBL6747367 | 0.87 | F2 (0.49) | F2PRSS2CTRCF10 | |
| SCHEMBL6846619 | 0.82 | F2 (0.52) | F2PRSS2CTRCF10KMT2A | |
| SCHEMBL6851400 | 0.77 | F2 (0.53) | F2PRSS2CTRCF10 | |
| SCHEMBL6929248 | 0.73 | F2 (0.46) | F2PRSS2CTRCF10 | |
| SCHEMBL6750764 | 0.73 | F2 (0.66) | F2 | |
| SCHEMBL6923341 | 0.73 | F2 (0.70) | F2PRSS2CTRC | |
| SCHEMBL5243760 | 0.72 | KMT2A (0.61) | AKR1C3PKLRAKR1C1CYP2C19KMT2A | |
| SCHEMBL6928378 | 0.72 | F2 (0.50) | F2PRSS2CTRCF10KMT2A | |
| SCHEMBL6745715 | 0.72 | F2 (0.50) | F2PRSS2CTRCF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944590-B1 | AMINOGUANIDINES AND ALKOXYGUANIDINES AS PROTEASE INHIBITORS | DIMENSIONAL PHARM INC (US) | 2002-03-20 | — | — | EP | disclosed |