Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 4/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77808 | 0.87 | CYP3A4 (0.42) | ALDH1A1MAPK1CYP3A4TSHRATM | |
| SCHEMBL29496845 | 0.85 | ALDH1A1 (0.43) | ALDH1A1MAPK1CYP3A4TSHRATM | |
| SCHEMBL76644 | 0.85 | ALDH1A1 (0.43) | ALDH1A1MAPK1CYP3A4TSHRATM | |
| SCHEMBL1720412 | 0.83 | ALDH1A1 (0.38) | ALDH1A1MAPK1CYP3A4TSHRATM | |
| SCHEMBL7691038 | 0.82 | PRSS1 (0.38) | ALDH1A1MAPK1CYP3A4TSHRATM | |
| SCHEMBL7072419 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MAPK1CYP3A4TSHRATM | |
| SCHEMBL6460885 | 0.81 | ALDH1A1 (0.40) | ALDH1A1MAPK1CYP3A4TSHRATM | |
| SCHEMBL6436270 | 0.79 | PRSS1 (0.35) | ALDH1A1MAPK1CYP3A4TSHRATM | |
| SCHEMBL20835340 | 0.78 | ALDH1A1 (0.42) | ALDH1A1MAPK1CYP3A4TSHRATM | |
| SCHEMBL284444 | 0.78 | CYP3A4 (0.56) | ALDH1A1MAPK1CYP3A4TSHRATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6486226-B2 | ACYLPHOSPHINE OXIDE PHOTOINITIATOR(S); LIGHTFAST RED, BLUE OR VIOLET ORGANIC PIGMENT(S); UNSATURATED CURABLE COMPOUND(S); CLEAR AND WHITE COATINGS, SCREEN INKS, GEL COATS, POWDER COATINGS, COMPOSITES, ADHESIVES AND LENSES | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-11-26 | — | — | US | disclosed |