Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA3 | P15088 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.39 |
| ▸ | GGH | Q92820 | 1/20 | 0.39 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1377537 | 0.83 | FOLH1 (0.52) | CPA3FOLH1NAALAD2GGHSRR | |
| SCHEMBL2368169 | 0.80 | CPA3 (0.43) | CPA3FOLH1NAALAD2GGHSRR | |
| SCHEMBL2368167 | 0.79 | CPA3 (0.45) | CPA3FOLH1NAALAD2GGHSRR | |
| SCHEMBL5051276 | 0.78 | FOLH1 (0.50) | CPA3FOLH1GGHKEAP1 | |
| SCHEMBL5053058 | 0.75 | FOLH1 (0.47) | CPA3FOLH1GGHSRR | |
| SCHEMBL5059834 | 0.74 | FOLH1 (0.46) | CPA3FOLH1 | |
| SCHEMBL1376074 | 0.74 | ACE (0.51) | FOLH1 | |
| SCHEMBL1374791 | 0.74 | GGH (0.52) | CPA3FOLH1GGH | |
| SCHEMBL5053099 | 0.73 | ACE (0.55) | FOLH1 | |
| SCHEMBL5051250 | 0.73 | MAPT (0.45) | CPA3FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479471-B1 | NOVEL PHOSPHONATE DERIVATIVES, HYDROXYPHOSPHINYL DERIVATIVES, AND PHOSPHORAMIDATE DERIVATIVES THAT INHIBIT N-ACETYLATED .ALPHA.-LINKED ACIDIC DIPEPTIDASE (NAALADASE) ENZYME ACTIVITY TO TREAT PROSTATE DISEASES | GUILFORD PHARMACEUTICALS INC. | 2002-11-12 | — | — | US | disclosed |