Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 16/20 | 0.62 |
| ▸ | ITGB1 | P05556 | 15/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7378504 | 0.96 | ITGA4 (0.59) | ITGA4ITGB1MEN1KMT2ABCHE | |
| SCHEMBL7427793 | 0.94 | ITGA4 (0.59) | ITGA4ITGB1KMT2ABCHEACHE | |
| SCHEMBL7426753 | 0.93 | ITGB1 (0.64) | ITGA4ITGB1MEN1KMT2ABCHE | |
| SCHEMBL7421722 | 0.91 | ITGB1 (0.61) | ITGA4ITGB1MEN1KMT2ABCHE | |
| SCHEMBL7425495 | 0.91 | ITGB1 (0.61) | ITGA4ITGB1MEN1KMT2ABCHE | |
| SCHEMBL7427104 | 0.90 | ITGB1 (0.57) | ITGA4ITGB1MEN1KMT2A | |
| SCHEMBL7428160 | 0.90 | ITGB1 (0.57) | ITGA4ITGB1MEN1KMT2ABCHE | |
| SCHEMBL7426542 | 0.89 | ITGB1 (0.59) | ITGA4ITGB1MEN1KMT2ABCHE | |
| SCHEMBL7590998 | 0.88 | ITGB1 (0.62) | ITGA4ITGB1MEN1KMT2ABCHE | |
| SCHEMBL7426813 | 0.88 | ITGA4 (0.49) | ITGA4ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |