Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GCGR | P47871 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7648479 | 0.82 | MAPT (0.53) | GAAMAPTALDH1A1L3MBTL1PTPN1 | |
| SCHEMBL7649211 | 0.79 | PRSS1 (0.43) | GAAMAPTALDH1A1HDAC8HDAC6 | |
| SCHEMBL7645206 | 0.79 | PRSS1 (0.43) | GAAMAPTALDH1A1HDAC1 | |
| SCHEMBL7646888 | 0.78 | ALDH1A1 (0.57) | MAPTALDH1A1L3MBTL1HDAC3HDAC1 | |
| SCHEMBL5605088 | 0.77 | GAA (0.66) | GAAMAPTALDH1A1PPARGL3MBTL1 | |
| SCHEMBL11331749 | 0.76 | GAA (0.70) | GAAMAPTALDH1A1PPARGL3MBTL1 | |
| SCHEMBL11112945 | 0.76 | GAA (0.70) | GAAMAPTALDH1A1PPARGL3MBTL1 | |
| SCHEMBL917492 | 0.76 | GAA (0.59) | GAAMAPTALDH1A1PPARGL3MBTL1 | |
| SCHEMBL1030950 | 0.75 | GAA (1.00) | GAAMAPTALDH1A1PPARGL3MBTL1 | |
| SCHEMBL7650078 | 0.75 | ALDH1A1 (0.64) | GAAMAPTALDH1A1L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100871-A1 | NEW COMPOUNDS USEFUL IN REFLUX DISEASE | ASTRAZENECA AB (SE) | 2002-12-19 | — | — | WO | claimed |
| WO-2002100871-A1 | NEW COMPOUNDS USEFUL IN REFLUX DISEASE | ASTRAZENECA AB (SE) | 2002-12-19 | — | — | WO | disclosed |