Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7108338 | 0.83 | ALDH1A1 (0.43) | HSD17B10CYP2C9GAAALDH1A1L3MBTL1 | |
| SCHEMBL11228867 | 0.80 | GAA (0.52) | ESR1CYP2C9ESR2GAAAR | |
| SCHEMBL12522902 | 0.79 | ESR1 (0.44) | ESR1ESR2ARTDP1TP53 | |
| SCHEMBL3355077 | 0.78 | CYP2C9 (0.45) | ESR1HSD17B10CYP2C9ESR2AR | |
| SCHEMBL26621253 | 0.78 | CYP2C9 (0.45) | ESR1HSD17B10CYP2C9ESR2AR | |
| SCHEMBL28879500 | 0.78 | ESR1 (0.46) | ESR1CYP2C9ESR2ARTDP1 | |
| SCHEMBL29185565 | 0.76 | HIF1A (0.47) | HSD17B10CYP2C9GAAKDM4EMAPT | |
| SCHEMBL5274794 | 0.76 | GAA (0.52) | ESR1CYP2C9ESR2GAAAR | |
| SCHEMBL16682793 | 0.76 | ESR1 (0.44) | ESR1HSD17B10CYP2C9ESR2GAA | |
| SCHEMBL25152388 | 0.74 | MAPT (0.51) | L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228135-A1 | STABILIZERS AND ANTIOZONANTS FOR ELASTOMERS | Ciba SC Holding AG (CH) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001029126-A1 | STABILIZERS AND ANTIOZONANTS FOR ELASTOMERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-04-26 | — | — | WO | disclosed |