Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 7/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 3/20 | 0.32 |
| ▸ | DRD4 | P21917 | 3/20 | 0.32 |
| ▸ | HRH1 | P35367 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8774021 | 0.68 | PNMT (0.46) | PNMTHTR2ANPC1RAB9AHTR7 | |
| SCHEMBL6650492 | 0.68 | PNMT (0.46) | PNMTHTR2ANPC1RAB9AHTR7 | |
| SCHEMBL633763 | 0.68 | PNMT (0.68) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL30606684 | 0.68 | PNMT (0.68) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL8734338 | 0.68 | KDM4E (0.33) | KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL6638923 | 0.68 | PNMT (0.37) | PNMTNPC1RAB9AHTR7HTR2B | |
| Iodide SCHEMBL3382482 | 0.67 | PNMT (0.52) | PNMTHTR2ANPC1RAB9AHTR7 | |
| Fluoride Ion SCHEMBL3384402 | 0.67 | PNMT (0.52) | PNMTHTR2ANPC1RAB9AHTR7 | |
| Hydrochloric Acid SCHEMBL30274953 | 0.67 | PNMT (0.52) | PNMTHTR2ANPC1RAB9AHTR7 | |
| Hydrochloric Acid SCHEMBL3385861 | 0.67 | PNMT (0.52) | PNMTHTR2ANPC1RAB9AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403734-B1 | POLYMERIZING ALPHA-OLEFIN BY CONTACTING WITH CATALYST SYSTEM COMPRISING BRIDGED FLUORENYL METALLOCENE CONTAINING METAL OF GROUP 4 OR 5 AND SUITABLE COCATALYST | PHILLIPS PETROLEUM COMPANY | 2002-06-11 | — | — | US | claimed |
| CN-1060176-C | Organometallic fluorenyl compounds, preparation, and use | PHILLIPS PETROLEUM CO (US) | 2001-01-03 | — | — | CN | disclosed |
| CN-1109472-A | Organometallic fluorenyl compounds, preparation, and use | PHILLIPS PETROLEUM CO (US) | 1995-10-04 | — | — | CN | disclosed |
| CN-1068829-A | Organometallic fluorenyl compounds and preparation thereof and application | PHILLIPS PETROLEUM CO (US) | 1993-02-10 | — | — | CN | disclosed |