Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 15/20 | 0.61 |
| ▸ | ITGA4 | P13612 | 15/20 | 0.61 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | CTSA | P10619 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426793 | 0.96 | ITGA4 (0.59) | ITGB1ITGA4ITGB7P2RX7CTSA | |
| SCHEMBL7392270 | 0.95 | ITGA4 (0.59) | ITGB1ITGA4ITGB7P2RX7CTSA | |
| SCHEMBL7561313 | 0.92 | ITGB1 (0.63) | ITGB1ITGA4ITGB7P2RX7 | |
| SCHEMBL7587137 | 0.91 | ITGB1 (0.61) | ITGB1ITGA4ITGB7P2RX7 | |
| SCHEMBL7587157 | 0.91 | ITGB1 (0.61) | ITGB1ITGA4ITGB7P2RX7 | |
| SCHEMBL7419462 | 0.91 | ITGA4 (0.61) | ITGB1ITGA4ITGB7P2RX7 | |
| SCHEMBL7389750 | 0.90 | ITGA4 (0.53) | ITGB1ITGA4ITGB7CTSA | |
| SCHEMBL7585955 | 0.90 | ITGB1 (0.57) | ITGB1ITGA4ITGB7KMT2A | |
| SCHEMBL7646545 | 0.90 | ITGB1 (0.60) | ITGB1ITGA4ITGB7P2RX7 | |
| SCHEMBL7476951 | 0.90 | ITGA4 (0.60) | ITGB1ITGA4MEN1KMT2AP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |