Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 6/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 6/20 | 0.45 |
| ▸ | CTSA | P10619 | 7/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7390822 | 1.00 | ITGB1 (0.45) | ITGB1ITGA4CTSAPOLBTSHR | |
| Trifluoroacetic Acid SCHEMBL5701085 | 0.96 | ITGB1 (0.42) | ITGB1ITGA4CTSAPOLBTSHR | |
| SCHEMBL7651698 | 0.92 | ITGB1 (0.49) | ITGB1ITGA4CTSASMN1; SMN2MAPT | |
| SCHEMBL7651701 | 0.92 | ITGB1 (0.49) | ITGB1ITGA4CTSASMN1; SMN2MAPT | |
| SCHEMBL7646244 | 0.89 | ITGA4 (0.47) | ITGB1ITGA4CTSASMN1; SMN2ITGB7 | |
| SCHEMBL7646241 | 0.89 | ITGA4 (0.47) | ITGB1ITGA4CTSASMN1; SMN2ITGB7 | |
| SCHEMBL7645886 | 0.88 | ITGB1 (0.44) | ITGB1ITGA4CTSASMN1; SMN2ITGB7 | |
| SCHEMBL7389044 | 0.88 | ITGB1 (0.44) | ITGB1ITGA4CTSASMN1; SMN2ITGB7 | |
| SCHEMBL7422471 | 0.88 | ITGB1 (0.49) | ITGB1ITGA4CTSAPOLBMAPT | |
| SCHEMBL7644620 | 0.88 | ITGB1 (0.49) | ITGB1ITGA4CTSAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | claimed |
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |