Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.53 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.53 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7646154 | 0.90 | SLC7A5 (0.47) | CYP4A11CYP4F2SLC7A5HDAC1CA14 | |
| SCHEMBL14415229 | 0.86 | CYP4A11 (0.68) | CYP4A11CYP4F2SLC7A5LOXL2DHODH | |
| SCHEMBL7646280 | 0.85 | SLC7A5 (0.43) | CYP4A11CYP4F2SLC7A5HDAC1HDAC3 | |
| SCHEMBL25046666 | 0.84 | L3MBTL1 (0.45) | HDAC1CA14HDAC3HDAC2NCOR2 | |
| SCHEMBL25048622 | 0.82 | HTR2C (0.42) | CYP4A11CYP4F2HDAC1CA14HDAC3 | |
| SCHEMBL25047672 | 0.82 | FDFT1 (0.47) | ACHE | |
| SCHEMBL30940803 | 0.82 | FDFT1 (0.47) | ACHE | |
| SCHEMBL25048105 | 0.82 | HDAC1 (0.44) | HDAC1CA14HDAC3HDAC2NCOR2 | |
| SCHEMBL31618048 | 0.81 | L3MBTL1 (0.38) | CYP4A11CYP4F2HDAC1CA14HDAC3 | |
| SCHEMBL7505386 | 0.81 | CYP4F2 (0.69) | CYP4A11CYP4F2SLC7A5LOXL2DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100871-A1 | NEW COMPOUNDS USEFUL IN REFLUX DISEASE | ASTRAZENECA AB (SE) | 2002-12-19 | — | — | WO | disclosed |