Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7649262 | 0.86 | VDR (0.38) | VDR | |
| SCHEMBL7647798 | 0.85 | VDR (0.39) | VDR | |
| SCHEMBL7615200 | 0.83 | VDR (0.52) | VDR | |
| SCHEMBL7648316 | 0.82 | VDR (0.38) | VDRESR2S1PR1S1PR5 | |
| SCHEMBL7611748 | 0.81 | VDR (0.33) | VDR | |
| SCHEMBL6563023 | 0.77 | VDR (0.61) | VDRESR2S1PR1S1PR5 | |
| SCHEMBL7610503 | 0.73 | VDR (0.42) | VDR | |
| SCHEMBL7606174 | 0.73 | VDR (0.53) | VDRS1PR1S1PR5 | |
| SCHEMBL7607761 | 0.72 | VDR (0.45) | VDRS1PR1S1PR5 | |
| SCHEMBL7606746 | 0.72 | VDR (0.35) | VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235777-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | claimed |
| WO-2001038303-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | claimed |