SCHEMBL7648736

SCHEMBL7648736

Cc1cn([C@H]2C[C@H](OC(=O)OCCc3c(Cl)cc(Cl)cc3[N+](=O)[O-])[C@@H](CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RNASE1 P07998 1/20 0.52
TK1 P04183 4/20 0.43
DTYMK P23919 1/20 0.43
TK2 O00142 2/20 0.42
LMNA P02545 2/20 0.42
TSHR P16473 2/20 0.42
ALB P02768 1/20 0.42
PKM P14618 1/20 0.42
BLM P54132 1/20 0.42
PMP22 Q01453 1/20 0.42
CYP2D6 P10635 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8719144 1.00 RNASE1 (0.52) RNASE1TK1DTYMKTK2LMNA
SCHEMBL7644753 0.94 RNASE1 (0.45) RNASE1TK1
SCHEMBL7648511 0.90 RNASE1 (0.56) RNASE1TK1DTYMKTK2LMNA
SCHEMBL8723702 0.90 RNASE1 (0.56) RNASE1TK1DTYMKTK2LMNA
SCHEMBL7646615 0.87 POLB (0.47)
SCHEMBL8719350 0.87 POLB (0.47)
SCHEMBL7645962 0.85 RNASE1 (0.48) RNASE1TK1
SCHEMBL8723685 0.84 RNASE1 (0.56) RNASE1TK1TK2LMNATSHR
SCHEMBL8722406 0.84 RNASE1 (0.56) RNASE1TK1TK2LMNATSHR
SCHEMBL7643824 0.84 RNASE1 (0.56) RNASE1TK1TK2LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0797580-B1 NUCLEOSIDE DERIVATIVES WITH PHOTOLABILE PROTECTIVE GROUPS PFLEIDERER WOLFGANG (DE) 2002-04-10 EP disclosed
US-5763599-A FOR LIGHT-CONTROLLED SYNTHESIS OF OLIGONUCLEOTIDES ON DNA CHIP Pfleiderer, Wolfgang (DE) 1998-06-09 US disclosed