SCHEMBL7648748

SCHEMBL7648748

CCOc1cc2c(cc1OC)C(=O)CC(C)(C)O2

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.52
ALDH1A1 P00352 6/20 0.48
GAA P10253 5/20 0.48
HPGD P15428 2/20 0.48
CASP1 P29466 2/20 0.48
HSD17B10 Q99714 2/20 0.48
GLA P06280 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
CASP7 P55210 1/20 0.46
MAPT P10636 1/20 0.46
MAOB P27338 10/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10402701 1.00 KDM4E (0.52) KDM4EALDH1A1GAAHPGDCASP1
SCHEMBL4243740 0.90 KDM4E (0.61) KDM4EALDH1A1GAAHPGDCASP1
SCHEMBL10509997 0.88 KDM4E (0.49) KDM4EALDH1A1GAAHPGDCASP1
SCHEMBL16774398 0.85 KDM4E (0.48) KDM4EALDH1A1GAAHPGDCASP1
SCHEMBL10403014 0.84 ALDH1A1 (0.52) KDM4EALDH1A1GAAHPGDCASP1
SCHEMBL6275678 0.84 MAOB (0.49) KDM4EALDH1A1GAAHPGDCASP1
SCHEMBL10510003 0.82 KDM4E (0.48) KDM4EALDH1A1GAAHPGDCASP1
SCHEMBL10608800 0.81 KDM4E (0.52) KDM4EALDH1A1GAAHPGDCASP1
SCHEMBL6279249 0.80 KDM4E (0.50) KDM4EALDH1A1GAAHPGDCASP1
SCHEMBL9206382 0.80 ALDH1A1 (0.51) KDM4EALDH1A1GAAHPGDCASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6461417-B1 Ink compositions XEROX CORPORATION 2002-10-08 US claimed
US-6117223-A Hot melt inks containing polyketones XEROX CORPORATION (US) 2000-09-12 US claimed
US-5663029-A DEVELOPMENT OF LATENT IMAGE, TRANSFERRING TO FORM RECORDING SHEETS, COATING A SUBSTRATE USING POLYMERS XEROX CORPORATION (US) 1997-09-02 US claimed
US-6461417-B1 Ink compositions XEROX CORPORATION 2002-10-08 US disclosed
US-6117223-A Hot melt inks containing polyketones XEROX CORPORATION (US) 2000-09-12 US disclosed
US-4968819-A CATALYTIC SELECTIVE ETHERIFICATION ALKALOIDA VEGYESZETI GYAR (HU) 1990-11-06 US disclosed
US-4866089-A 7-ALKOXY-8-METHOXY-2,2-DIMETHYL-2H-CHROMENES; INSECTICIDES, NEMATOCIDES ALKALOIDA VEGYESZETI GYAR (HU) 1989-09-12 US disclosed
EP-0129636-B1 PROCESS FOR THE PREPARATION OF CHROMEN DERIVATIVES ALKALOIDA VEGYéSZETI GYáR (HU) 1989-01-04 EP disclosed
EP-0271550-A1 BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES AND COMPOSITIONS CONTAINING THEM ALKALOIDA VEGYéSZETI GYáR (HU) 1988-06-22 EP disclosed
WO-1988000197-A1 BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES AND COMPOSITIONS CONTAINING THEM ALKALOIDA VEGYE^´SZETI GYA^´R (HU) 1988-01-14 WO disclosed
EP-0129636-A1 Process for the preparation of chromen derivatives ALKALOIDA VEGYéSZETI GYáR (HU) 1985-01-02 EP disclosed