Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 15/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CTRC | Q99895 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6925569 | 0.90 | ALDH1A1 (0.41) | MEN1KMT2ATSHRMAPK1SMN1; SMN2 | |
| SCHEMBL6926975 | 0.88 | F2 (0.37) | F2PRSS2F10ALDH1A1CTRC | |
| SCHEMBL6930340 | 0.82 | TSHR (0.45) | MEN1KMT2ATSHRMAPK1SMN1; SMN2 | |
| SCHEMBL6754993 | 0.81 | F2 (0.48) | F2PRSS2F10CTRC | |
| SCHEMBL6747717 | 0.79 | SMN1; SMN2 (0.37) | SMN1; SMN2F2PRSS2ALDH1A1CTRC | |
| SCHEMBL7649160 | 0.75 | MEN1 (0.46) | MEN1KMT2ATSHRMAPK1SMN1; SMN2 | |
| SCHEMBL6749285 | 0.74 | F2 (0.43) | MEN1KMT2AF2PRSS2F10 | |
| SCHEMBL6749785 | 0.73 | F2 (0.47) | MEN1KMT2ATSHRMAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7650543 | 0.72 | F2 (0.47) | F2PRSS2F10CTRC | |
| SCHEMBL6747809 | 0.71 | F2 (0.52) | F2PRSS2F10CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944590-B1 | AMINOGUANIDINES AND ALKOXYGUANIDINES AS PROTEASE INHIBITORS | DIMENSIONAL PHARM INC (US) | 2002-03-20 | — | — | EP | disclosed |