Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 7/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346780 | 0.76 | BRD4 (0.51) | CYP3A4PDE10AMAPTBRD4ALDH1A1 | |
| SCHEMBL8015316 | 0.75 | IDH1 (0.48) | IDH1CYP3A4MAPTALDH1A1CA2 | |
| SCHEMBL3048607 | 0.72 | MAPT (0.55) | CYP3A4MAPTALDH1A1POLBKDM4E | |
| SCHEMBL29864658 | 0.72 | MAPT (0.55) | CYP3A4MAPTALDH1A1POLBKDM4E | |
| SCHEMBL10704920 | 0.71 | IDH1 (0.45) | IDH1CYP3A4MAPTBRD4ALDH1A1 | |
| SCHEMBL23610040 | 0.70 | BRD4 (0.49) | CYP3A4MAPTBRD4ALDH1A1KDM4E | |
| SCHEMBL14081505 | 0.70 | BRD4 (0.49) | CYP3A4MAPTBRD4ALDH1A1KDM4E | |
| SCHEMBL29485027 | 0.70 | BRD4 (0.49) | CYP3A4MAPTBRD4ALDH1A1KDM4E | |
| SCHEMBL28799220 | 0.70 | MAPT (0.53) | CYP3A4MAPTBRD4ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL10324019 | 0.70 | MAPT (0.53) | CYP3A4MAPTBRD4ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020065315-A1 | Ion channel modulating agents | POSEIDON PHARMACEUTICALS A/S (DK) | 2002-05-30 | — | — | US | claimed |
| EP-1178963-A1 | ION CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2002-02-13 | — | — | EP | claimed |
| WO-2000069823-A1 | ION CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2000-11-23 | — | — | WO | claimed |
| US-20020065315-A1 | Ion channel modulating agents | POSEIDON PHARMACEUTICALS A/S (DK) | 2002-05-30 | — | — | US | disclosed |
| EP-1178963-A1 | ION CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000069823-A1 | ION CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2000-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020065315-A1 | Ion channel modulating agents | KCNN1, KCNN3, KCNN2 | IDH1 2973/4885CYP3A4 3142/4885PDE10A 523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.