Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7650101 | 0.83 | TSHR (0.34) | TSHRCA12CA2CA9CA1 | |
| SCHEMBL7644146 | 0.81 | TSHR (0.47) | TSHRCA12CA14LMNAALDH1A1 | |
| SCHEMBL15951711 | 0.76 | TSHR (0.48) | TSHRCA12CA14CA2CA9 | |
| SCHEMBL15951714 | 0.75 | TSHR (0.47) | TSHRCA12CA14CA2CA9 | |
| SCHEMBL6930781 | 0.74 | PPARD (0.54) | TSHRCA12CA2CA9CA1 | |
| SCHEMBL11494792 | 0.72 | CYP3A4 (0.45) | TSHRCA12CA14CA2CA9 | |
| SCHEMBL15951683 | 0.72 | TSHR (0.44) | TSHRCA12CA14CA2CA9 | |
| SCHEMBL11203182 | 0.72 | TSHR (0.52) | TSHRCA12CA14CA2CA9 | |
| SCHEMBL7645867 | 0.71 | CA12 (0.34) | CA12CA2CA9CA1 | |
| SCHEMBL28336971 | 0.69 | TSHR (0.48) | TSHRLMNAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002008235-A1 | MEDICAMENT FOR ORAL APPLICATION, CONTAINING AMINOPROPYL PHOSPHONIC ACID ESTERS AS AN ACTIVE INGREDIENT | JOMAA PHARMAKA GMBH (DE) | 2002-01-31 | — | — | WO | disclosed |