Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7649205 | 0.83 | TSHR (0.41) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL7649338 | 0.80 | TSHR (0.40) | TSHRPPARDHSD17B10MGAMGAA | |
| SCHEMBL6930781 | 0.77 | PPARD (0.54) | TSHRPPARDGAACA12CA1 | |
| SCHEMBL10011234 | 0.69 | TSHR (0.39) | TSHRPPARDHSD17B10MGAMGAA | |
| SCHEMBL9445918 | 0.69 | PPARD (0.44) | TSHRPPARDHSD17B10CA12CA1 | |
| SCHEMBL11436912 | 0.68 | PPARD (0.55) | TSHRPPARDCA12CA1CA2 | |
| SCHEMBL10395205 | 0.68 | TSHR (0.60) | TSHRPPARDHSD17B10MGAMGAA | |
| SCHEMBL10011806 | 0.68 | TSHR (0.43) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL11519577 | 0.68 | TSHR (0.43) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL10067496 | 0.68 | TPI1 (0.54) | TSHRHSD17B10MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002008235-A1 | MEDICAMENT FOR ORAL APPLICATION, CONTAINING AMINOPROPYL PHOSPHONIC ACID ESTERS AS AN ACTIVE INGREDIENT | JOMAA PHARMAKA GMBH (DE) | 2002-01-31 | — | — | WO | disclosed |