SCHEMBL7649263

SCHEMBL7649263

[CH2]C(C)(C)CCCC(C)(C)CCCC

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28172303 0.92 TSHR (0.33) TSHR
SCHEMBL42740 0.89
SCHEMBL17607504 0.83 TSHR (0.32) TSHR
SCHEMBL8897968 0.83 TSHR (0.43) LMNATSHR
SCHEMBL99628 0.80
SCHEMBL27781294 0.80 TSHR (0.40) LMNATSHR
SCHEMBL2946715 0.80
SCHEMBL306916 0.79 TSHR (0.32) LMNATSHR
SCHEMBL1971287 0.79 LMNA (0.30) LMNATSHR
SCHEMBL2255900 0.78 TSHR (0.47) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6492364-B1 Triazolo and derivatives as chemokine inhibitors TORAY INDUSTRIES, INC. (JP) 2002-12-10 US disclosed
US-4549992-A Antihypertensive amides USV PHARMACEUTICAL CORP. (US) 1985-10-29 US disclosed