SCHEMBL7649264

SCHEMBL7649264

c1ccc(C(c2ccccc2)C2CCCNC2)cc1

nearest known ligand 0.52

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 13/20 0.43
SLC6A4 P31645 13/20 0.43
SLC6A3 Q01959 13/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8983761 0.98 SLC6A2 (0.42) SLC6A2SLC6A4SLC6A3
SCHEMBL23848782 0.91 SLC6A2 (0.47) SLC6A2SLC6A4SLC6A3
SCHEMBL25501912 0.91 SLC6A2 (0.44) SLC6A2SLC6A4SLC6A3
SCHEMBL11771618 0.89 SLC6A2 (0.53) SLC6A2SLC6A4SLC6A3
SCHEMBL3662366 0.87 SLC6A2 (0.56) SLC6A2SLC6A4
SCHEMBL19121854 0.86 SLC6A2 (0.44) SLC6A2SLC6A4SLC6A3
SCHEMBL973412 0.82 GBA1 (0.45) SLC6A2SLC6A4SLC6A3
SCHEMBL10677201 0.82 SLC6A2 (0.48) SLC6A2SLC6A4SLC6A3
SCHEMBL30096734 0.82 SLC6A2 (0.39) SLC6A2SLC6A4SLC6A3
SCHEMBL23832800 0.82 SLC6A2 (0.39) SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1149214-C Triazolo gerivatives and chemokine inhibitors containing the same as the active ingredient ������������ʽ���� 2004-05-12 CN disclosed
US-6492364-B1 Triazolo and derivatives as chemokine inhibitors TORAY INDUSTRIES, INC. (JP) 2002-12-10 US disclosed
CN-1293674-A Triazolo gerivatives and chemokine inhibitors containing the same as the active ingredient TORAY INDUSTRIES (JP) 2001-05-02 CN disclosed
EP-1067130-A1 TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT TORAY INDUSTRIES, INC. (JP) 2001-01-10 EP disclosed
US-4306063-A 4-Substituted 3,5-morpholinediones MCNEIL LABORATORIES, INC. (US) 1981-12-15 US disclosed
US-4256891-A (2-Amino-2-oxoethoxy)acetic acid compounds MCNEIL LABORATORIES, INC. (US) 1981-03-17 US disclosed
US-4203991-A (Piperidino oxoethoxy)acetic acid compounds, compositions and methods MCNEILAB, INC. (US) 1980-05-20 US disclosed
US-4197315-A (2-Amino-2-oxoethoxy)acetic acid compounds, compositions and methods MCNEIL LABORATORIES, INC. (US) 1980-04-08 US disclosed
US-4191828-A CATALYTIC HYDROGENATION OF 2-(2,2-DIPHENYLETHYL)PYRIDINE RICHARDSON-MERRELL INC. (US) 1980-03-04 US disclosed
US-4123538-A (2-Amino-2-oxoethoxy)acetic acid compounds, compositions and methods MCNEIL LABORATORIES, INCORPORATED (US) 1978-10-31 US disclosed
US-4069222-A CATALYTIC HYDROGENATION OF CORRESPONDING PYRIDINE COMPOUND, RANEY NICKEL CATALYST RICHARDSON-MERRELL INC. (US) 1978-01-17 US disclosed