Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | PAM | P19021 | 2/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 6/20 | 0.45 |
| ▸ | PPARD | Q03181 | 6/20 | 0.45 |
| ▸ | PPARA | Q07869 | 6/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TLR2 | O60603 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | FABP4 | P15090 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8198788 | 0.94 | CES2 (0.69) | CES2MEN1KMT2ATHRBHTT | |
| SCHEMBL501889 | 0.94 | CES2 (0.69) | CES2MEN1KMT2ATHRBHTT | |
| SCHEMBL7249862 | 0.94 | CES2 (0.69) | CES2MEN1KMT2ATHRBHTT | |
| SCHEMBL7763197 | 0.94 | CES2 (0.69) | CES2MEN1KMT2ATHRBHTT | |
| SCHEMBL3296171 | 0.94 | CES2 (0.69) | CES2MEN1KMT2ATHRBHTT | |
| SCHEMBL1603697 | 0.94 | CES2 (0.69) | CES2MEN1KMT2ATHRBHTT | |
| SCHEMBL8626082 | 0.94 | CES2 (0.69) | CES2MEN1KMT2ATHRBHTT | |
| SCHEMBL21611691 | 0.94 | CES2 (0.69) | CES2MEN1KMT2ATHRBHTT | |
| SCHEMBL21611665 | 0.94 | CES2 (0.69) | CES2MEN1KMT2ATHRBHTT | |
| SCHEMBL4651569 | 0.94 | CES2 (0.69) | CES2MEN1KMT2ATHRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934078-B1 | PERMEATION ENHANCERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS, DEVICES, AND METHODS | ALZA CORP (US) | 2002-12-18 | — | — | EP | disclosed |