SCHEMBL7649656

SCHEMBL7649656

Cc1cc(C(=N)c2nccs2)c(C)cc1Oc1cccc(C(F)(F)F)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TEAD1 P28347 3/20 0.40
F10 P00742 1/20 0.39
BRAF P15056 1/20 0.38
KDR P35968 1/20 0.38
PRKD3 O94806 2/20 0.37
PRKCG P05129 2/20 0.37
PRKCB P05771 2/20 0.37
PRKCA P17252 2/20 0.37
PRKCH P24723 2/20 0.37
PRKCI P41743 2/20 0.37
PRKCE Q02156 2/20 0.37
PRKCQ Q04759 2/20 0.37
PRKCZ Q05513 2/20 0.37
PRKCD Q05655 2/20 0.37
PRKD1 Q15139 2/20 0.37
RAB9A P51151 2/20 0.37
KDM4E B2RXH2 2/20 0.36
ALDH1A1 P00352 1/20 0.36
POLB P06746 1/20 0.36
MAPT P10636 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7952610 0.78 F10 (0.51) TEAD1F10RAB9AKDM4EALDH1A1
SCHEMBL14141360 0.75 TEAD1 (0.39) TEAD1BRAFKDRPRKD3PRKCG
SCHEMBL7649660 0.75 TEAD1 (0.39) TEAD1BRAFKDRPRKD3PRKCG
SCHEMBL4608873 0.69 MAPT (0.55) TEAD1F10RAB9AKDM4EALDH1A1
SCHEMBL6141347 0.68 TEAD1 (0.41) TEAD1F10PRKD3PRKCGPRKCB
SCHEMBL22719771 0.66 TEAD1 (0.52) TEAD1RAB9AKDM4EALDH1A1POLB
SCHEMBL22719742 0.66 L3MBTL1 (0.48) TEAD1F10RAB9AKDM4EALDH1A1
SCHEMBL25472566 0.66 TEAD1 (0.55) TEAD1F10RAB9AKDM4EALDH1A1
SCHEMBL14586640 0.66 NPSR1 (0.50) TEAD1RAB9AKDM4EALDH1A1POLB
SCHEMBL30553089 0.65 TEAD1 (0.49) TEAD1F10KDM4EALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2002205979-A FUNGICIDAL PHENYLIMINE DERIVATIVE AVENTIS CROPSCIENCE SA 2002-07-23 JP disclosed