Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 7/20 | 0.74 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.64 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.64 |
| ▸ | MLNR | O43193 | 1/20 | 0.64 |
| ▸ | HTR2A | P28223 | 1/20 | 0.64 |
| ▸ | HTR2C | P28335 | 1/20 | 0.64 |
| ▸ | HRH1 | P35367 | 1/20 | 0.64 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.64 |
| ▸ | DRD3 | P35462 | 1/20 | 0.64 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.64 |
| ▸ | HTR2B | P41595 | 1/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.57 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27661811 | 0.88 | CHRM3 (0.58) | CHRM3CHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL1088155 | 0.85 | CHRM3 (1.00) | CHRM3CHRM1CHRM2MLNRHTR2A | |
| SCHEMBL10518474 | 0.85 | CHRM3 (0.54) | CHRM3CHRM1CHRM2MLNRHTR2A | |
| SCHEMBL4243782 | 0.85 | CHRM3 (0.69) | CHRM3CHRM1CHRM2MLNRHTR2A | |
| SCHEMBL27550848 | 0.83 | CHRM3 (0.73) | CHRM3CHRM1CHRM2MLNRHTR2A | |
| Hydrochloric Acid SCHEMBL27826728 | 0.83 | CHRM3 (0.71) | CHRM3CHRM1CHRM2MLNRHTR2A | |
| SCHEMBL4735652 | 0.82 | CHRM3 (1.00) | CHRM3CHRM1CHRM2MLNRHTR2A | |
| SCHEMBL13701451 | 0.82 | CHRM3 (0.70) | CHRM3CHRM1CHRM2MLNRHTR2A | |
| SCHEMBL4245281 | 0.82 | CHRM3 (0.66) | CHRM3CHRM1CHRM2MLNRHTR2A | |
| SCHEMBL13701453 | 0.82 | CHRM3 (0.70) | CHRM3CHRM1CHRM2MLNRHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6482837-B1 | Antimuscarinic compounds and methods for treatment of bladder diseases | UNIVERSITY OF ROCHESTER | 2002-11-19 | — | — | US | disclosed |