Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10104241 | 0.83 | KMT2A (0.48) | ALDH1A1MAPK1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL10036633 | 0.83 | ALDH1A1 (0.62) | ALDH1A1HPGDNPC1TP53NFKB1 | |
| SCHEMBL7268240 | 0.83 | ALDH1A1 (0.57) | ALDH1A1HPGDNPC1TP53NFKB1 | |
| SCHEMBL4579345 | 0.81 | — | — | |
| SCHEMBL14241665 | 0.81 | — | — | |
| SCHEMBL5566252 | 0.81 | — | — | |
| SCHEMBL4579342 | 0.81 | — | — | |
| SCHEMBL226350 | 0.81 | — | — | |
| SCHEMBL5143720 | 0.81 | — | — | |
| SCHEMBL18677214 | 0.79 | MAPT (0.37) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6488909-B1 | RADIODIAGNOSIS AND RADIOTHERAPY; COUPLED TO SUBSTANCES THAT ACCUMULATE IN THE DISEASED TISSUE | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-12-03 | — | — | US | disclosed |