Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27994435 | 0.93 | UGT2B7 (0.55) | UGT2B7MEN1KMT2AATMSLC6A2 | |
| SCHEMBL30033673 | 0.81 | UGT2B7 (0.68) | UGT2B7MEN1KMT2AATMSLC6A2 | |
| SCHEMBL434216 | 0.81 | UGT2B7 (0.68) | UGT2B7MEN1KMT2AATMSLC6A2 | |
| SCHEMBL600527 | 0.81 | UGT2B7 (0.68) | UGT2B7MEN1KMT2AATMSLC6A2 | |
| SCHEMBL517247 | 0.77 | UGT2B7 (0.63) | UGT2B7MEN1KMT2AATMCYP2D6 | |
| SCHEMBL445001 | 0.77 | UGT2B7 (1.00) | UGT2B7MEN1KMT2AATMSLC6A2 | |
| SCHEMBL29609979 | 0.77 | UGT2B7 (1.00) | UGT2B7MEN1KMT2AATMSLC6A2 | |
| SCHEMBL11015437 | 0.77 | UGT2B7 (0.52) | UGT2B7MEN1KMT2AATMSLC6A2 | |
| SCHEMBL15352903 | 0.77 | UGT2B7 (0.63) | UGT2B7MEN1KMT2AATMSLC6A2 | |
| SCHEMBL110360 | 0.77 | UGT2B7 (1.00) | UGT2B7MEN1KMT2AATMSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002514184-A | — | — | 2002-05-14 | — | — | JP | claimed |
| EP-1005348-A1 | NAALADASE COMPOSITIONS AND METHODS FOR TREATING GLUTAMATE ABNORMALITY AND EFFECTING NEURONAL ACTIVITY IN ANIMALS | GUILFORD PHARMACEUTICALS INC. (US) | 2000-06-07 | — | — | EP | claimed |
| WO-1998013046-A1 | NAALADASE COMPOSITIONS AND METHODS FOR TREATING GLUTAMATE ABNORMALITY AND EFFECTING NEURONAL ACTIVITY IN ANIMALS | GUILFORD PHARMACEUTICALS INC. (US) | 1998-04-02 | — | — | WO | claimed |
| CN-105189493-A | Novel Pyrazole Derivatives | MOCHIDA PHARM CO LTD | 2015-12-23 | — | — | CN | disclosed |
| CN-105153146-A | Novel 3-hydroxyisothiazole 1-oxide derivative | MOCHIDA PHARM CO LTD | 2015-12-16 | — | — | CN | disclosed |
| CN-103517898-B | Novel 3-hydroxyisothiazole 1-oxide derivatives | MOCHIDA PHARMACEUTICAL CO.,LTD. (JP) | 2015-09-30 | — | — | CN | disclosed |
| CN-104710381-A | Novel 3-hydroxy-5-arylisothiazole derivative | MOCHIDA PHARM CO LTD | 2015-06-17 | — | — | CN | disclosed |
| CN-102712610-B | Novel 3-hydroxy-5-arylisothiazole derivatives | MOCHIDA PHARM CO LTD | 2015-03-04 | — | — | CN | disclosed |
| CN-104271571-A | Tetrazolinone compound and use thereof | SUMITOMO CHEMICAL CO | 2015-01-07 | — | — | CN | disclosed |
| CN-103517898-A | Novel 3-hydroxyisothiazole 1-oxide derivatives | MOCHIDA PHARM CO LTD | 2014-01-15 | — | — | CN | disclosed |
| CN-102666490-A | Aminopyridine compound | UBE INDUSTRIES | 2012-09-12 | — | — | CN | disclosed |
| CN-102498101-A | Aniline compounds | UBE INDUSTRIES | 2012-06-13 | — | — | CN | disclosed |
| CN-100497345-C | 2, 3-dihydro-6-nitroimidazolo [2,1-b] oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-1878777-A | 2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2006-12-13 | — | — | CN | disclosed |
| CN-1142909-C | Indole derivatives with antiviral activity | ��Ұ����ҩ��ʽ���� | 2004-03-24 | — | — | CN | disclosed |
| CN-1087298-C | Bisphosphite compound, process for producing the same, and hydroformylation process using the same | MITSUBISHI CHEM CORP (JP) | 2002-07-10 | — | — | CN | disclosed |
| CN-1294580-A | Indole derivatives with antiviral activity | SHIONOGI & CO (JP) | 2001-05-09 | — | — | CN | disclosed |
| CN-1292782-A | Novel unsymmetrically substituted carboxylic acid derivatives, method for producing them, and their use as mixed ETA/ETB-receptor antagonists | BASF AG (DE) | 2001-04-25 | — | — | CN | disclosed |
| CN-1167769-A | Bisphosphite compound, process for producing the same, and hydroformylation process using the same | MITSUBISHI CHEM CORP (JP) | 1997-12-17 | — | — | CN | disclosed |