Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 6/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.39 |
| ▸ | F10 | P00742 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6836445 | 0.89 | ADRA2A (0.43) | ADRA2AADRA2BADRA2CPDE4APDE4B | |
| Fumaric Acid SCHEMBL7650107 | 0.88 | PDE4A (0.40) | ADRA2AADRA2BADRA2CPDE4APDE4B | |
| Fumaric Acid SCHEMBL7650112 | 0.88 | PDE4A (0.40) | ADRA2AADRA2BADRA2CPDE4APDE4B | |
| SCHEMBL6836546 | 0.87 | ADRA2A (0.45) | ADRA2AADRA2BADRA2CPDE4APDE4B | |
| SCHEMBL6836665 | 0.77 | PDE4D (0.60) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6839392 | 0.76 | PDE4D (0.45) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6839191 | 0.75 | PDE4D (0.48) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6966847 | 0.75 | PDE4D (0.44) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6836584 | 0.75 | PDE4D (0.47) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6954408 | 0.74 | PDE4D (0.46) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395738-B1 | ANTIINFLAMMATORY, ANTIALLERGENS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |