Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 10/20 | 0.68 |
| ▸ | FNTB | P49356 | 10/20 | 0.68 |
| ▸ | SIRT2 | Q8IXJ6 | 9/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7658679 | 0.89 | FNTA (0.53) | FNTAFNTBSIRT2 | |
| SCHEMBL8121014 | 0.85 | FNTA (0.72) | FNTAFNTB | |
| SCHEMBL7653520 | 0.85 | FNTA (0.78) | FNTAFNTB | |
| SCHEMBL7654669 | 0.82 | FNTA (0.65) | FNTAFNTB | |
| SCHEMBL7656283 | 0.81 | FNTA (0.77) | FNTAFNTB | |
| SCHEMBL7658680 | 0.80 | FNTA (0.45) | FNTAFNTBSIRT2 | |
| SCHEMBL7651934 | 0.79 | FNTA (0.77) | FNTAFNTB | |
| SCHEMBL7656712 | 0.76 | FNTA (0.67) | FNTAFNTB | |
| SCHEMBL7656240 | 0.75 | FNTA (1.00) | FNTAFNTB | |
| SCHEMBL7656698 | 0.75 | FNTA (0.77) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384061-B1 | HYDANTOIN COMPOUNDS REPRESENTED BY FORMULA (I) WHICH SHOWS AN INHIBITORY ACTIVITY AGAINST FARNESYL TRANSFERASE, AND THUS CAN BE USED AS AN ANTI-CANCER AGENT, OR PHARMACEUTICALLY ACCEPTABLE SALTS | LG CHEMICAL LTD. (KR) | 2002-05-07 | — | — | US | disclosed |