SCHEMBL7654669

SCHEMBL7654669

CCOC(=O)CN1C(=O)N(CCCc2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)C(=O)C1(C)c1cccc2ccccc12

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 20/20 0.65
FNTB P49356 20/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7658679 0.83 FNTA (0.53) FNTAFNTB
SCHEMBL7658680 0.83 FNTA (0.45) FNTAFNTB
SCHEMBL8129842 0.83 FNTA (0.67) FNTAFNTB
SCHEMBL7650126 0.82 FNTA (0.68) FNTAFNTB
SCHEMBL7661615 0.77 FNTA (0.56) FNTAFNTB
SCHEMBL7655285 0.73 FNTA (0.76) FNTAFNTB
SCHEMBL4383636 0.73 SIRT2 (0.45)
SCHEMBL9259069 0.72 CYP4F2 (0.46)
SCHEMBL7658359 0.71 FNTA (0.73) FNTAFNTB
SCHEMBL6922674 0.71 FNTA (0.50) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6384061-B1 HYDANTOIN COMPOUNDS REPRESENTED BY FORMULA (I) WHICH SHOWS AN INHIBITORY ACTIVITY AGAINST FARNESYL TRANSFERASE, AND THUS CAN BE USED AS AN ANTI-CANCER AGENT, OR PHARMACEUTICALLY ACCEPTABLE SALTS LG CHEMICAL LTD. (KR) 2002-05-07 US disclosed