Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SNCA | P37840 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7650281 | 1.00 | CYP1A2 (0.48) | CYP1A2CYP2D6TSHRCYP2C19SMN1; SMN2 | |
| SCHEMBL7527657 | 0.94 | TSHR (0.50) | CYP1A2CYP2D6TSHRCYP2C19SMN1; SMN2 | |
| SCHEMBL7527663 | 0.94 | TSHR (0.50) | CYP1A2CYP2D6TSHRCYP2C19SMN1; SMN2 | |
| SCHEMBL7648625 | 0.92 | APP (0.46) | CYP1A2CYP2D6TSHRCYP2C19ALDH1A1 | |
| SCHEMBL7648628 | 0.92 | APP (0.46) | CYP1A2CYP2D6TSHRCYP2C19ALDH1A1 | |
| SCHEMBL7530323 | 0.92 | KCNK2 (0.47) | ALDH1A1SNCAMITFAPPKCNK2 | |
| SCHEMBL7644381 | 0.92 | CYP1A2 (0.43) | CYP1A2CYP2D6TSHRCYP2C19SMN1; SMN2 | |
| SCHEMBL7644374 | 0.92 | CYP1A2 (0.43) | CYP1A2CYP2D6TSHRCYP2C19SMN1; SMN2 | |
| SCHEMBL7647418 | 0.91 | APP (0.49) | SMN1; SMN2ALDH1A1HPGDSNCAAPP | |
| SCHEMBL7647393 | 0.91 | APP (0.49) | SMN1; SMN2ALDH1A1HPGDSNCAAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479548-B2 | P-(BENZOYLAMINO)STILBENE DERIVATIVES | TELIK, INC. | 2002-11-12 | — | — | US | disclosed |